Trial reportGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024
Tolerance to residual astigmatism of an isofocal intraocular lens.
Trial report in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Adaptive-Optics-Based Simulation of Astigmatism Effects on Visual Acuity with Enhanced Monofocal Intraocular Lenses.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Observational
- Navigating the Lens Labyrinth: A Practical Approach to Intraocular Lens Classification and Selection.Ophthalmology and therapy · 2025Article
- Clinical Tolerance to Induced Astigmatism in Eyes Implanted with a Single Extended Depth of Focus Intraocular Lens (AT LARAClinical ophthalmology (Auckland, N.Z.) · 2025Article
- Clinical Tolerance to Experimentally Induced with-the-Rule and Against-the-Rule Astigmatism After Implantation of an Extended Depth-of-Focus Intraocular Lens: A Defocus-Curve Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Clinical Outcomes of a Multicenter Study Following Implantation of an Isofocal Optic IOL with Double C-Loop Haptics.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Visual and Refractive Outcomes After Implantation of an Isofocal Optic-Design Intraocular Lens with Double C-Loop Haptics in Japanese Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Optical quality in vitro and in vivo of an extended depth-of-focus intraocular lens with isofocal design.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Validation of Clinical Protocol of Astigmatism Induction in Pseudophakic Patients.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Evaluation of Visual Outcomes, Postoperative Angle Alpha, and Angle Kappa After Implantation of Isofocal Intraocular Lenses.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- A New Methodology for Evaluating the Potential Impact of Residual Refractive Astigmatism in Pseudophakic Patients.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- The BVI ISOPUREFrontiers in ophthalmology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo evaluate the impact of residual astigmatism on the optical and visual performance of an enhanced-monofocal isofocal intraocular lens (EM Isopure, BVI medical, Belgium) compared to a monofocal one (Micropure, BVI medical, Belgium).
methodsLaboratory investigation and prospective, comparative and randomized clinical study. Optical quality was assessed on an optical bench for 2.0, 3.0, and 4.5 mm pupils. The effect of residual astigmatism was investigated from through-focus images recorded with increasing amounts of regular positive astigmatism induced with a deformable mirror. To evaluate the impact of residual astigmatism, 28 eyes of 28 patients were randomly assigned to either group. Residual astigmatism was induced with positive and negative cylinder lenses at 90 and 180°. Visual acuity (VA) was measured at each step.
resultsThe optical performance of both IOLs was quite similar for 2.0 and 3.0 mm pupils. For 4.5-mm pupil, the EM Isopure showed a significant reduction of its optical quality in comparison with the monofocal IOL. When visual performance was evaluated, no statistically significant differences were found for any power of induced astigmatism. More differences were found when positive induced astigmatism was compared within each group, and VA was better when the astigmatism was induced at 180° vs. 90°. The greatest differences were found for and induced positive astigmatism of + 1.50D (p = 0.009 for Isopure and p = 0.023 for Micropure).
conclusionsThe tolerance to residual astigmatism of the EM Isopure lens is similar to that of a reference monofocal lens with pupils up to 3.5 mm.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.