Evidence map›Paper›PMID 37950363›Full record

ArticleCNS neuroscience & therapeutics2024

Association between nutritional status and gait performance in Alzheimer's disease.

Mingyue He, Tenghong Lian, Peng Guo, Yanan Zhang, Yue Huang, Jing Qi, Jinghui Li, Huiying Guan, Dongmei Luo, Zhan Liu and 9 more

Open access · goldAbstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 2 countries.

Mingyue HeDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0000-0001-8825-3771
Tenghong LianCenter for Cognitive Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Peng GuoCenter for Cognitive Neurology, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yanan ZhangDepartment of Blood Transfusion, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yue HuangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jing QiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jinghui LiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Huiying GuanDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Dongmei LuoDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zhan LiuDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Weijia ZhangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Zijing ZhengDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hao YueDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jing LiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Wenjing ZhangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ruidan WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Fan ZhangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Xiaomin WangDepartment of Physiology, Capital Medical University, Beijing, China.
Wei ZhangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CN

Funding

Beijing Healthcare Research Project, China JING-15-2Capital Clinical Characteristic Application Research Z121107001012161Capital Medical University, China 10JL49Capital Medical University, China 14JL15Capital Medical University, China 2015-JL-PT-X04Capital's Funds for Health Improvement and Research (CFH) 2022-2-2048Excellent Personnel Training Project of Beijing, China 20071D0300400076High Level Technical Personnel Training Project of Beijing Health System, China 2009-3-26Key Project of Natural Science Foundation of Beijing, China 4161004Key Technology R&D Program of Beijing Municipal Education Commission kz201610025030National Key Research and Development Program of China 2016YFC1306000National Key Research and Development Program of China 2016YFC1306300National Natural Science Foundation of China 30770745National Natural Science Foundation of China 81071015National Natural Science Foundation of China 81571229National Natural Science Foundation of China 81970992National Natural Science Foundation of China 82201639Natural Science Foundation of Beijing, China 7082032Natural Science Foundation of Capital Medical University, Beijing, China PYZ2018077Project of Beijing Institute for Brain Disorders BIBD-PXM2013_014226_07_000084Project of Construction of Innovative Teams and Teacher Career Development for Universities and Colleges Under Beijing Municipality IDHT20140514Project of Scientific and Technological Development of Traditional Chinese Medicine in Beijing JJ2018-48
6 · The paper itself

Abstract

aimsThis study aimed to comprehensively explore the nutrition and gait of AD patients at different stages and the relationship between them.

methodsA total of 85 AD patients were consecutively enrolled in this cross-sectional study and divided into the mild cognitive impairment (MCI) due to AD (AD-MCI) and the dementia due to AD (AD-D) groups. Demographic information, nutritional status, and gait performance were compared between the two groups, and the correlation between nutritional status and gait performance was subsequently analyzed by Pearson and Spearman correlation analyses.

resultsThe AD-D group had lower scores on Mini-Nutritional Assessment (MNA) and MNA

conclusionsAD patients at the dementia stage had worse nutritional status and gait performance than those at the MCI stage, which was associated with worse global cognition and activities of daily living. Poorer nutritional status was associated with higher gait variability in patients at the MCI stage and with poorer gait performance in patients at the dementia stage. Early identification and intervention of patients with nutritional risk or malnutrition may improve gait performance, thus reducing the risk of falling and cognitive decline, as well as the mortality.

Indexed as

Alzheimer DiseaseCognitive DysfunctionActivities of Daily LivingCross-Sectional StudiesFolic AcidGaitHomocysteineHumansNitrogenNutritional StatusUreaVitaminsFolic AcidHomocysteineNitrogenUreaVitaminsAlzheimer's diseasedementiagait performancegait variabilitymild cognitive impairmentnutritional status

Identifiers

PMID37950363
PMCPMC11017406
OpenAlexW4388599714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.