ArticleJournal of cardiothoracic surgery2023
Surgical repair of post myocardial infarction ventricular septal defect: a retrospective analysis of a single institution experience.
Article in Journal of cardiothoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Article
- Simultaneous Percutaneous Ventricular Septal Closure and Mitral Valve Repair in Postinfarction Mechanical Complications: Case Report.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Acute myocardial infarction with ventricular septal rupture: Clinical characteristics, prognosis factors, and treatment strategies.World journal of cardiology · 2025Review
- Deferring Percutaneous Coronary Intervention in Subacute STEMI With Rare Mechanical Complications.JACC. Case reports · 2025Article
- Post-myocardial infarction ventricular septal defects: incidence and treatment trends during and after the COVID-19 pandemic.Scientific reports · 2025Article
- Correction: Surgical repair of post myocardial infarction ventricular septal defect: a retrospective analysis of a single institution experience.Journal of cardiothoracic surgery · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
introductionVentricular septal defect (VSD) is a mechanical complication of acute myocardial infarction (MI) with a very high mortality, despite advances in surgical and circulatory support. The tremendous hemodynamic disturbance and the severely fragile myocardium render surgical repair a great challenge. The optimal time of surgical repair with or without circulatory support is still controversial.
objectiveThe aim of this study is to review our experience with early surgical repair of post-MI VSD in a single major cardiac institution in China.
methodsFrom January 2013 to October 2020, 9consecutive patients presented to our emergency department with a diagnosis of post-MI VSD. Among them, 8 were male, and the mean age was 58 ± 7years. The mean VSD size was 22.5 ± 5.7 mm. In all patients, an intra-aortic balloon pump (IABP)was inserted immediately after admission to cardiac surgery service. All patients were operated at a mean of 3.3 ± 2.9 days, and 4 within 24 h of the rupture (range 1 to 9 days post-VSD). In 5 cases, the VSD was located superiorly, and 4 cases in the posterior septum.
resultsThe overall 30-day mortality was 11% (1/9). Coronary angiography was performed in all nine patients, four with single vessel disease had coronary stents implanted, and the other five received concomitant coronary artery bypass grafting during VSD repair surgery. There was no death in all 5 patients with anterior septal perforation. One patient with posterior septal perforation died in the operating room due to bleeding from the ventriculotomy site. Three survived patients were diagnosed with a small residual defect and mild left to right shunt post-repair. However, no further intervention was required, and patients remained asymptomatic (Killip II in 1 and III in 2).
conclusionIn our experience, immediate insertion of IABP and hemodynamic stabilization with early surgical intervention of VSD repair and concomitant coronary revascularization provided an 89% survival rate.
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