Evidence map›Paper›PMID 37950259›Full record

ArticleBMC ophthalmology2023

Comparison of corneal and lens density measurements obtained by Pentacam and CASIA2 in myopes.

Yijia Xu, Yuhao Ye, Yiyong Xian, Lingling Niu, Xingtao Zhou, Jing Zhao

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yijia Xu *Department of Ophthalmology, NHC Key Laboratory of Myopia, Laboratory of Myopia, Eye and ENT Hospital of Fudan University, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.
Yuhao Ye *Department of Ophthalmology, NHC Key Laboratory of Myopia, Laboratory of Myopia, Eye and ENT Hospital of Fudan University, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.
Yiyong XianDepartment of Ophthalmology, NHC Key Laboratory of Myopia, Laboratory of Myopia, Eye and ENT Hospital of Fudan University, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.
Lingling NiuDepartment of Ophthalmology, NHC Key Laboratory of Myopia, Laboratory of Myopia, Eye and ENT Hospital of Fudan University, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.
Xingtao ZhouDepartment of Ophthalmology, NHC Key Laboratory of Myopia, Laboratory of Myopia, Eye and ENT Hospital of Fudan University, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China. doctzhouxingtao@163.com.
Jing ZhaoDepartment of Ophthalmology, NHC Key Laboratory of Myopia, Laboratory of Myopia, Eye and ENT Hospital of Fudan University, Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China. zhaojing_med@163.com.
Shanghai Eye Disease Prevention & Treatment Center · CNFudan University · CNShanghai Clinical Research Center · CN

Funding

Clinical Research Plan of SHDC SHDC2020CR1043BHealthy Young Talents Project of Shanghai Municipal Health Commission 2022YQ015National Natural Science Foundation of China 82271119Project of Shanghai Science and Technology 20410710100Project of Shanghai Xuhui District Science and Technology XHLHGG202104
6 · The paper itself

Abstract

purposeTo investigate the agreement between Pentacam and CASIA2 in the evaluation of corneal densities (CDs) and lens densities (LDs) in myopes.

methodsFifty-three patients (106 eyes) underwent comprehensive ophthalmologic examinations. CDs and LDs were measured using Pentacam and CASIA2, respectively, based on the grayscale percentage of the obtained images. Agreement between Pentacam and CASIA2 was evaluated using the consistency intraclass correlation coefficient (ICC) and represented using Bland-Altman plots.

resultsCompared to Pentacam, CASIA2 showed significantly higher CD and LD values in all measured zones. The ICC of the average CD and LD measured by the Pentacam and CASIA2 were 0.726 and 0.757, respectively. The ICC values of all corneal zones and lenses were above 0.7, except for the measurement of the cornea in the 0-2 mm zone (0.455), suggesting good consistency between the two devices, whose results were of different levels of linear correlation. Bland-Altman plots showed mean percentages of 3.93% for the points falling outside the limits of agreement among the densitometry results. The ICCs in different age groups were similar, but the agreement was poorer in the high myopia group (low and moderate myopia, CD: 0.739, LD: 0.753; high myopia, CD: 0.621, LD: 0.760).

conclusionsCASIA2 demonstrated good consistency with Pentacam in the measurement of CD and LD, except for measurement of CD in the central cornea and in high myopia. Despite difference in the numerical results compared with Pentacam, which made the two devices uninterchangeable, CASIA2 provides a reliable alternative densitometric measurement method.

Indexed as

Lens, CrystallineMyopiaCorneaHumansCASIA2Corneal densitylens densityMyopiaPentacam

Identifiers

PMID37950259
PMCPMC10636911
OpenAlexW4388573855

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.