Evidence map›Paper›PMID 37950220›Full record

ArticleBMC musculoskeletal disorders2023

Preliminary exploration of the biomechanical properties of three novel cervical porous fusion cages using a finite element study.

Zhi Xu, Yuwan Li, Weijun Huang, Ziru Wang, Xing Xu, Shoujin Tian

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Zhi XuDepartment of Orthopedic, Zhangjiagang Fifth People's Hospital, Zhangjiagang, 215600, Jiangsu, China. 2224183819@qq.com.
Yuwan LiDepartment of Orthopedic, Peking University Third Hospital, Beijing, 100191, China.
Weijun HuangDepartment of Orthopedic, Shangyu Third Hospital, Shangyu, 312300, Zhejiang, China.
Ziru WangClinical Medical College, Wannan Medical College, Wuhu, 241000, Anhui, China.
Xing XuDepartment of Medicine, Zhijin People's Hospital, Zhijin, 552100, Guizhou, China.
Shoujin TianDepartment of Orthopedic, Zhangjiagang First People's Hospital, Zhangjiagang, 215600, Jiangsu, China. tiansurgeon@163.com.
First Affiliated Hospital of Wannan Medical College · CNFirst Affiliated Hospital Zhejiang University · CNSoochow University · CNZhangjiagang First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorous cages are considered a promising alternative to high-density cages because their interconnectivity favours bony ingrowth and appropriate stiffness tuning reduces stress shielding and the risk of cage subsidence.

methodsThis study proposes three approaches that combine macroscopic topology optimization and micropore design to establish three new types of porous cages by integrating lattices (gyroid, Schwarz, body-centred cubic) with the optimized cage frame. Using these three porous cages along with traditional high-density cages, four ACDF surgical models were developed to compare the mechanical properties of facet articular cartilage, discs, cortical bone, and cages under specific loads.

resultsThe facet joints in the porous cage groups had lower contact forces than those in the high-density cage group. The intervertebral discs in all models experienced maximum stress at the C5/6 segment. The stress distribution on the cortical bone surface was more uniform in the porous cage groups, leading to increased average stress values. The gyroid, Schwarz, and BCC cage groups showed higher average stress on the C5 cortical bone. The average stress on the surface of porous cages was higher than that on the surface of high-density cages, with the greatest difference observed under the lateral bending condition. The BCC cage demonstrated favourable mechanical stability.

conclusionThe new porous cervical cages satifies requirements of low rigidity and serve as a favourable biological scaffold for bone ingrowth. This study provides valuable insights for the development of next-generation orthopaedic medical devices.

Indexed as

Intervertebral DiscSpinal DiseasesSpinal FusionBiomechanical PhenomenaCervical VertebraeFinite Element AnalysisHumansPorosityAdditive manufacturingAnterior cervical discectomy and fusionPorous structureStress shieldingTopological optimization

Identifiers

PMID37950220
PMCPMC10636970
OpenAlexW4388570262

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.