Evidence map›Paper›PMID 37950188›Full record

ArticleBMC palliative care2023

Xerostomia in patients with advanced cancer: a scoping review of clinical features and complications.

Maria Walsh, Norah Fagan, Andrew Davies

Registry-linked trialOpen access · goldAbstract readScoping Review
In one paragraph

Article in BMC palliative care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06465628 (Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06465628 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients: a Randomized Controlled Trial

TypeinterventionalSponsorThe University of Hong KongRan2024 to 2027Enrolled126ConditionsHead and Neck Cancer, XerostomiaArmsSelf-administered acupressure, Oral health education
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Relationship between salivary inflammatory mediators and oral dryness during chemotherapy in patients with cancer: a cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Review
  5. Taste alterations in patients with cancer: an overview and recommendations for future research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Maria WalshMarymount University Hospital & Hospice, Curraheen, Ireland.
Norah FaganOur Lady's Hospice & Care Services, Dublin, Ireland.
Andrew DaviesTrinity College Dublin, University College Dublin & Our Lady's Hospice Dublin, Dublin, Ireland. andavies@tcd.ie.ORCID http://orcid.org/0000-0003-4207-4799
Our Lady's Hospital · IEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this project was to review the literature on dry mouth / xerostomia in patients with advanced cancer, with the objectives being to determine its prevalence, clinical features, and complications.

methodsStandard methodology was used to conduct this scoping review. Detailed searches of the Medline, Embase, CINAHL, and PsycInfo databases were conducted to identify relevant studies: eligible studies had to include patients with advanced cancer, and to contain details of clinical features and/or complications of xerostomia. Commercial bibliographic / systematic review software was used to support the process.

resultsForty-three studies were discovered from the database and hand searches. The studies included 23 generic symptom studies, eight "symptom cluster" studies, nine oral symptom / problem studies, and three xerostomia-specific studies. In depth data is described on the clinical features and complications of xerostomia, and on the "symptom clusters" including xerostomia, in this cohort of patients.

conclusionThis review discovered a relatively small number of focused studies (involving a similarly small number of patients). Nonetheless, it demonstrates that xerostomia is a very common problem in patients with advanced cancer and is often associated with significant morbidity (and impairment of quality of life).

Indexed as

NeoplasmsXerostomiaHumansPrevalenceQuality of LifeSyndromeDry mouthNeoplasmsPalliative careXerostomia

Identifiers

PMID37950188
PMCPMC10638744
OpenAlexW4388582829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.