Evidence map›Paper›PMID 37949975›Full record

Trial reportEye (London, England)2024

Risk factors for corneal abrasions in Nepal: a community-based study.

Sylvia R Brekke, Puspa Giri, Raghunandan Byanju, Sangita Pradhan, Gopal Bhandari, Sadhan Bhandari, Ram Prasad Kandel, Bimal Poudyal, John A Gonzales, Muthiah Srinivasan and 6 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Sylvia R Brekke *Francis I Proctor Foundation, University of California, San Francisco, CA, USA.
Puspa Giri *Bharatpur Eye Hospital, Bharatpur, Nepal.
Raghunandan ByanjuBharatpur Eye Hospital, Bharatpur, Nepal.
Sangita PradhanBharatpur Eye Hospital, Bharatpur, Nepal.
Gopal BhandariBharatpur Eye Hospital, Bharatpur, Nepal.
Sadhan BhandariBharatpur Eye Hospital, Bharatpur, Nepal.
Ram Prasad KandelSeva Foundation, Berkeley, CA, USA.
Bimal PoudyalBharatpur Eye Hospital, Bharatpur, Nepal.
John A GonzalesFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
Muthiah SrinivasanDepartment of Cornea and Refractive Surgery, Aravind Eye Hospital, Madurai, India.
Madan UpadhyayBP Eye Foundation, Children's Hospital for Eye, Ear, and Rehabilitation Services (CHEERS), Kathmandu, Nepal.
John P WhitcherFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.
Kieran S O'BrienFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-1962-5321
Thomas M LietmanFrancis I Proctor Foundation, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-8216-0240
Jeremy D KeenanFrancis I Proctor Foundation, University of California, San Francisco, CA, USA. jeremy.keenan@ucsf.edu.ORCID http://orcid.org/0000-0002-7118-1457
VIEW Trial Study Group
Biratnagar Eye Hospital · NPUniversity of California, San Francisco · USAravind Eye Hospital · INSeva Foundation · USTilganga Institute of Ophthalmology · NP

Funding

Village Integrated Eye Workers TrialU10EY022880 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LIETMAN, THOMAS M · 2013 to 2017
$2.3M
NEI NIH HHS U10 EY022880
6 · The paper itself

Abstract

backgroundSouth Asia is experiencing rapid urbanization, which may be changing the risk factor profile for ocular trauma. The objective of this study was to compare risk factors for traumatic corneal abrasions in rural versus urban Nepal, and to assess if any risk factors were associated with a poor outcome.

methodsIn a prospective, cross-sectional, community-based study performed as part of a cluster-randomized trial, community health workers from Nepal were trained to diagnose and treat traumatic corneal abrasions. Participants with an abrasion were invited to complete a risk factor survey. The main exposure variable was the object of eye injury, stratified by rural-urban residence. The main outcome measure was a lack of corneal healing after a three-day course of antimicrobials.

resultsOf 3657 participants diagnosed with a corneal abrasion, 2265 completed a survey. Eye trauma occurred most frequently during agricultural activities. The most common object of injury was vegetative matter, accounting for approximately 40% of injuries in rural, peri-urban, and urban communities. Wood injuries were more common in rural communities (24%) compared with urban or peri-urban communities (13%). Eye injury from an animal was more likely to result in a non-healing corneal abrasion after 3 days of treatment compared with other types of trauma (prevalence ratio 2.59, 95%CI 1.16-5.76).

conclusionsHealth promotion activities for prevention of corneal ulcers in Nepal should focus on agricultural trauma in both rural and urban areas. Community members experiencing eye trauma from an animal may benefit from early referral to an eye clinic.

Indexed as

Corneal InjuriesCross-Sectional StudiesHumansNepalProspective StudiesRisk Factors

Identifiers

PMID37949975
PMCPMC10966037
OpenAlexW4388566482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.