ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024
A Cortical Mechanism Linking Saliency Detection and Motor Reactivity in Rhesus Monkeys.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Focused Ultrasound Neuromodulation of Salience Network Hubs Selectively Enhances Anxiety-Relevant Autonomic Habituation in Humans.Biological psychiatry global open science · 2026Article
- A two-system theory of sensory-evoked brain responses.Brain : a journal of neurology · 2026Review
- Mapping and modulating brain dynamics in aging and neurodegeneration with electroencephalography and integrated neurotechnologies in primates.Frontiers in neuroscience · 2026Review
- The Extralemniscal System Modulates Early Somatosensory Cortical Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Dorsolateral Prefrontal Cortex: A High-level Hub for Allostatic Cardiovascular Control.Current neuropharmacology · 2025Review
- Involuntary motor responses are elicited both by rare sounds and rare pitch changes.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
Sudden and surprising sensory events trigger neural processes that swiftly adjust behavior. To study the phylogenesis and the mechanism of this phenomenon, we trained two male rhesus monkeys to keep a cursor inside a visual target by exerting force on an isometric joystick. We examined the effect of surprising auditory stimuli on exerted force, scalp electroencephalographic (EEG) activity, and local field potentials (LFPs) recorded from the dorsolateral prefrontal cortex. Auditory stimuli elicited (1) a biphasic modulation of isometric force, a transient decrease followed by a corrective tonic increase, and (2) EEG and LFP deflections dominated by two large negative-positive waves (N70 and P130). The EEG potential was symmetrical and maximal at the scalp vertex, highly reminiscent of the human "vertex potential." Electrocortical potentials and force were tightly coupled: the P130 amplitude predicted the magnitude of the corrective force increase, particularly in the LFPs recorded from deep rather than superficial cortical layers. These results disclose a phylogenetically preserved corticomotor mechanism supporting adaptive behavior in response to salient sensory events.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.