Evidence map›Paper›PMID 37949472›Full record

ArticleBMJ open diabetes research & care2023

Ethnic disparities in progression rates for sight-threatening diabetic retinopathy in diabetic eye screening: a population-based retrospective cohort study.

Abraham Olvera-Barrios, Christopher G Owen, John Anderson, Alasdair N Warwick, Ryan Chambers, Louis Bolter, Yue Wu, Roshan Welikala, Jiri Fajtl, Sarah A Barman and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open diabetes research & care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Cohort Profile: The North East London Diabetes Study (NELDS).International journal of epidemiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 2 countries.

Abraham Olvera-BarriosNIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, UK arudnick@sgul.ac.uk dr.olvera.a@gmail.com.ORCID 0000-0002-3305-4465
Christopher G OwenPopulation Health Research Institute, St. George's University of London, London, UK.ORCID 0000-0003-1135-5977
John AndersonDiabetes, Homerton Healthcare NHS Foundation Trust, London, UK.ORCID 0000-0002-2355-9742
Alasdair N WarwickNIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Ryan ChambersDiabetes, Homerton Healthcare NHS Foundation Trust, London, UK.
Louis BolterDiabetes, Homerton Healthcare NHS Foundation Trust, London, UK.
Yue WuDepartment of Ophthalmology, University of Washington, Seattle, Washington, USA.
Roshan WelikalaSchool of Computer Science and Mathematics, Kingston University, London, UK.
Jiri FajtlSchool of Computer Science and Mathematics, Kingston University, London, UK.
Sarah A BarmanSchool of Computer Science and Mathematics, Kingston University, London, UK.
Paolo RemagninoDepartment of Computer Science, Durham University, Durham, UK.
Emily Y ChewDivision of Epidemiology and Clinical Applications, NEI/NIH, Bethesda, Maryland, USA.
Frederick L FerrisOphthalmic Research Consultants, Charlotte, North Carolina, USA.
Aroon D HingoraniInstitute of Cardiovascular Science, University College London, London, UK.
Reecha SofatDepartment of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.
Aaron Y LeeDepartment of Ophthalmology, University of Washington, Seattle, Washington, USA.
Catherine EganNIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Adnan TufailNIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Alicja R RudnickaPopulation Health Research Institute, St. George's University of London, London, UK arudnick@sgul.ac.uk dr.olvera.a@gmail.com.ORCID 0000-0003-0369-8574
ARIAS Research Group
Moorfields Eye Hospital NHS Foundation Trust · GBHomerton University Hospital NHS Foundation Trust · GBKingston University · GBSt George's, University of London · GBUniversity of Liverpool · GBUniversity of Washington · USDurham University · GBResearch Applications (United States) · US

Funding

Department of Health AI_HI200008Wellcome TrustWellcome Trust 224390/Z/21/Z
6 · The paper itself

Abstract

introductionThe English Diabetic Eye Screening Programme (DESP) offers people living with diabetes (PLD) annual eye screening. We examined incidence and determinants of sight-threatening diabetic retinopathy (STDR) in a sociodemographically diverse multi-ethnic population. RESEARCH DESIGN AND

methodsNorth East London DESP cohort data (January 2012 to December 2021) with 137 591 PLD with no retinopathy, or non-STDR at baseline in one/both eyes, were used to calculate STDR incidence rates by sociodemographic factors, diabetes type, and duration. HR from Cox models examined associations with STDR.

resultsThere were 16 388 incident STDR cases over a median of 5.4 years (IQR 2.8-8.2; STDR rate 2.214, 95% CI 2.214 to 2.215 per 100 person-years). People with no retinopathy at baseline had a lower risk of sight-threatening diabetic retinopathy (STDR) compared with those with non-STDR in one eye (HR 3.03, 95% CI 2.91 to 3.15, p<0.001) and both eyes (HR 7.88, 95% CI 7.59 to 8.18, p<0.001). Black and South Asian individuals had higher STDR hazards than white individuals (HR 1.57, 95% CI 1.50 to 1.64 and HR 1.36, 95% CI 1.31 to 1.42, respectively). Additionally, every 5-year increase in age at inclusion was associated with an 8% reduction in STDR hazards (p<0.001).

conclusionsEthnic disparities exist in a health system limited by capacity rather than patient economic circumstances. Diabetic retinopathy at first screen is a strong determinant of STDR development. By using basic demographic characteristics, screening programmes or clinical practices can stratify risk for sight-threatening diabetic retinopathy development.

Indexed as

Diabetes MellitusDiabetic RetinopathyHumansIncidenceLondonMass ScreeningRetrospective Studiesblindnessdiabetic retinopathyethnic groupshealthcare disparities

Identifiers

PMID37949472
PMCPMC10649497
OpenAlexW4388575921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.