Evidence map›Paper›PMID 37949372›Full record

ArticleThe Journal of hospital infection2024

COVID-19-related mortality and hospital admissions in the VIVALDI study cohort: October 2020 to March 2023.

O Stirrup, M Krutikov, B Azmi, I Monakhov, A Hayward, A Copas, L Shallcross

Open access · hybridAbstract read

In one paragraph

Article in The Journal of hospital infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

2.2field-weighted citation impact, top 11% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

O StirrupInstitute for Global Health, University College London, London, UK. Electronic address: oliver.stirrup@ucl.ac.uk.

M KrutikovUCL Institute of Health Informatics, London, UK.

B AzmiUCL Institute of Health Informatics, London, UK.

I MonakhovUK Health Security Agency, London, UK.

A HaywardUCL Institute of Epidemiology & Healthcare, London, UK; Health Data Research UK, London, UK.

A CopasInstitute for Global Health, University College London, London, UK.

L ShallcrossUCL Institute of Health Informatics, London, UK.

University College London · GBHealth Data Research UK · GBUK Health Security Agency

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term-care facilities (LTCFs) were heavily affected by COVID-19 early in the pandemic, but the impact of the virus has reduced over time with vaccination campaigns and build-up of immunity from prior infection.

objectivesTo evaluate the mortality and hospital admissions associated with SARS-CoV-2 in LTCFs in England over the course of the VIVALDI study, from October 2020 to March 2023.

methodsWe included residents aged ≥65 years from participating LTCFs who had available follow-up time within the analysis period. We calculated incidence rates (IRs) of COVID-19-linked mortality and hospital admissions per calendar quarter, along with infection fatality ratios (IFRs, within 28 days) and infection hospitalization ratios (IHRs, within 14 days) following positive SARS-CoV-2 test.

resultsA total of 26,286 residents were included, with at least one positive test for SARS-CoV-2 in 8513 (32.4%). The IR of COVID-19-related mortality peaked in the first quarter (Q1) of 2021 at 0.47 per 1000 person-days (1 kpd) (around a third of all deaths), in comparison with 0.10 per 1 kpd for Q1 2023 which had a similar IR of SARS-CoV-2 infections. There was a fall in observed IFR for SARS-CoV-2 infections from 24.9% to 6.7% between these periods, with a fall in IHR from 12.1% to 8.8%. The population had high overall IRs for mortality for each quarter evaluated, corresponding to annual mortality probability of 28.8-41.3%.

conclusionsStandardized real-time monitoring of hospitalization and mortality following infection in LTCFs could inform policy on the need for non-pharmaceutical interventions to prevent transmission.

Indexed as

COVID-19Health FacilitiesHospitalizationHospitalsHumansSARS-CoV-2Care homesCOVID-19Infection fatality ratioInfection hospitalization ratioSARS-CoV-2

Identifiers

PMID37949372

DOI10.1016/j.jhin.2023.10.021

PMCPMC10927615

OpenAlexW4388487132

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.