Evidence map›Paper›PMID 37948001›Full record

Observational studyGeneral thoracic and cardiovascular surgery2024

Hemodynamic predictors of negative false lumen remodeling after frozen elephant trunk for acute aortic dissection.

Yusuke Takei, Shohei Miyazaki, Kohei Suzuki, Shunsuke Saito, Hayato Oogaki, Yuki Muraoka, Takeshi Ogasawara, Masahiro Tezuka, Ikuko Shibasaki, Hirotsugu Fukuda

Abstract readObservational Study
In one paragraph

Observational study in General thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusuke TakeiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University Graduate School of Medicine, 880 Kitakobayashi, Mibu-machi, Shimotuga-gun, Tochigi, 321-0293, Japan. y-takei@dokkyomed.ac.jp.ORCID http://orcid.org/0000-0002-1307-2164
Shohei MiyazakiCardio Flow Design, Inc., Chiyoda, Tokyo, Japan.
Kohei SuzukiCardio Flow Design, Inc., Chiyoda, Tokyo, Japan.
Shunsuke SaitoCardio Flow Design, Inc., Chiyoda, Tokyo, Japan.
Hayato OogakiDepartment of Radiology, Dokkyo Medical University Hospital, Mibu-machi, Tochigi, Japan.
Yuki MuraokaDepartment of Radiology, Dokkyo Medical University Hospital, Mibu-machi, Tochigi, Japan.
Takeshi OgasawaraMathematics and Statistics Section, Department of Fundamental Education, Dokkyo Medical University, Mibu-machi, Tochigi, Japan.
Masahiro TezukaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University Graduate School of Medicine, 880 Kitakobayashi, Mibu-machi, Shimotuga-gun, Tochigi, 321-0293, Japan.
Ikuko ShibasakiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University Graduate School of Medicine, 880 Kitakobayashi, Mibu-machi, Shimotuga-gun, Tochigi, 321-0293, Japan.
Hirotsugu FukudaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University Graduate School of Medicine, 880 Kitakobayashi, Mibu-machi, Shimotuga-gun, Tochigi, 321-0293, Japan.

Funding

Japan Agency for Medical Research and Development JP20he1302022j0003
6 · The paper itself

Abstract

objectiveWe evaluated the blood flow within the downstream aortic false lumen after frozen elephant trunk repair for acute aortic dissection and identified hemodynamic predictors of false lumen expansion and negative false lumen remodeling using four-dimensional flow magnetic resonance imaging.

methodsThirty-one patients (Stanford type A, n = 28; Stanford type B, n = 3) with patent false lumen who underwent frozen elephant trunk procedures for acute aortic dissection were included in this observational study. Each patient underwent computed tomography during the follow-up period and four-dimensional flow magnetic resonance imaging within 3 postoperative months. The false lumen volumetric expansion rate was calculated using computed tomography data. The direction and the rate of flow in the lower descending aortic false lumen were analyzed. Negative false lumen remodeling was defined as a volumetric increase of > 10% from the baseline volume.

resultsNegative false lumen remodeling had developed in 6 of the 31 patients during the observation period. Most of the false lumen flows were biphasic during systole. The range between peak and nadir flow rates was associated with the false lumen volumetric expansion rate (β coefficient = 6.77; p < 0.01, R

conclusionsThe range between peak and nadir flow rates may serve as a hemodynamic predictor of negative false lumen remodeling, enabling further treatment for patients at risk of expansion in the downstream aorta.

Indexed as

Aortic DissectionBlood Vessel Prosthesis ImplantationHemodynamicsAcute DiseaseAgedAorta, ThoracicAortic AneurysmAortic Aneurysm, ThoracicAortographyBlood Flow VelocityComputed Tomography AngiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsFour-dimensional flow magnetic resonance imagingFrozen elephant trunkNegative false lumen remodeling

Identifiers

PMID37948001
PMCPMC11127806

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.