Evidence map›Paper›PMID 37947985›Full record

ReviewInternational urology and nephrology2024

Obesity and glomerular filtration rate.

Paula Schwartz, Maria M Capotondo, Miranda Quaintenne, Guido M Musso-Enz, Gustavo Aroca-Martinez, Carlos G Musso

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. The aging-related GFR decline in Chinese healthy elderly.International urology and nephrology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Paula SchwartzInternal Medicine Division. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Maria M CapotondoInternal Medicine Division. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Miranda QuaintennePhysiology Department, Instituto Universitario del Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Guido M Musso-EnzFacultad de Medicina, Universidad Catolica Argentina, Buenos Aires, Argentina.
Gustavo Aroca-MartinezFacultad de Ciencias de la Salud, Universidad Simon Bolivar, Barranquilla, Colombia.
Carlos G MussoPhysiology Department, Instituto Universitario del Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. carlos.musso@hospitalitaliano.org.ar.ORCID http://orcid.org/0000-0001-8666-1130
Hospital Italiano de Buenos Aires · ARPontificia Universidad Católica Argentina · ARUniversidad Simón Bolívar · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity has received considerable attention in general medicine and nephrology over the last few years. This condition increases the risk of metabolic syndrome, diabetes mellitus, hypertension, and dyslipidemia, which are the main risk factors for developing chronic kidney disease (CKD). Kidney damage caused by obesity can be explained by many mechanisms, such as sympathetic nervous and renin-angiotensin-aldosterone systems activation, mechanical stress, hormonal unbalance, as well as inflammatory cytokines production. Even though creatinine-based glomerular filtration rate (GFR) equations in obese individuals have been validated (Salazar-Corcoran and CKD-MCQ), changes in body weight after bariatric surgery (BS) leads to changes in creatininemia, affecting its reliability. Thus, an average between creatine and cystatin-based GFR equations would be more appropriate in this setting. Bariatric surgery can reverse diabetes mellitus and improve hypertension, which are the main causes of CKD. Conclusion: GFR can be affected by obesity and BS, and its value should be cautiously evaluated in this setting.

Indexed as

Diabetes MellitusHypertensionRenal Insufficiency, ChronicCreatinineGlomerular Filtration RateHumansObesityReproducibility of ResultsCreatinineBariatric surgeryGlomerular filtration rateObesity

Identifiers

PMID37947985
OpenAlexW4388573058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.