Evidence map›Paper›PMID 37947983›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2024

Prevalence, characteristics, and risk factors of venous thromboembolism in patients with brain tumor undergoing craniotomy: a meta-analysis.

Qingping Zeng, Guangyu Lu, Jing Yuan, Jiali Ding, Juan Chen, Xianru Gao, Yujia Huang, Tian Shi, Hailong Yu, Hongbin Ni and 1 more

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Predictive Model of Risk Factors for Secondary Venous Thromboembolism in Patients After Craniotomy.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qingping ZengSchool of Nursing, Medical College of Yangzhou University, Yangzhou University, Yangzhou, China.
Guangyu LuSchool of Public Health, Medical College of Yangzhou University, Yangzhou University, Yangzhou, China.
Jing YuanDepartment of Echocardiography, Northern Jiangsu People's Hospital, Yangzhou, China.
Jiali DingSchool of Nursing, Medical College of Yangzhou University, Yangzhou University, Yangzhou, China.
Juan ChenSchool of Nursing, Medical College of Yangzhou University, Yangzhou University, Yangzhou, China.
Xianru GaoSchool of Nursing, Medical College of Yangzhou University, Yangzhou University, Yangzhou, China.
Yujia HuangDepartment of Neuro Intensive Care Unit, Clinical Medical College of Yangzhou University, Yangzhou, China.
Tian ShiDepartment of Neuro Intensive Care Unit, Clinical Medical College of Yangzhou University, Yangzhou, China.
Hailong YuDepartment of Neuro Intensive Care Unit, Clinical Medical College of Yangzhou University, Yangzhou, China.
Hongbin NiDepartment of Neurosurgery, Nanjing Drum Tower Hospital, School of Medicine, Clinical College of Nanjing Medical University, Nanjing, 210008, Jiangsu, China. glyy110@163.com.
Yuping LiDepartment of Neuro Intensive Care Unit, Clinical Medical College of Yangzhou University, Yangzhou, China. yupingli@yzu.edu.cn.ORCID http://orcid.org/0000-0002-4527-2582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrain tumor patients undergoing craniotomy are significantly associated with the development of venous thromboembolism (VTE), while the contributing factors remains controversial. Our study aimed to investigate the prevalence and risk factors for VTE in postoperational brain tumor patients.

methodsWe searched the PubMed, Embase, Web of Science, Medline, and Cochrane Library databases from their inception to July 2023. Article selection, data extraction, and study quality assessment were performed independently by two reviewers. Publication bias was assessed using Egger's and Begg's tests. Stata 15.0 software was used for data analysis.

resultsA total of 25 studies were considered, with a total of 49,620 brain tumor individuals. The pooled prevalence of VTE during hospitalization in postoperational brain tumor patients was 9% [95% CI: (0.08, 0.10)]. Moreover, our results demonstrated that patients with VTE were older than those without VTE [mean difference [MD] = 8.14, 95% CI: (4.97, 11.30)]. The following variables were significantly associated with VTE: prior history of VTE [OR = 7.81, 95% CI: (3.62, 16.88)], congestive heart failure [OR = 2.33, 95% CI: (1.08-5.05)], diabetes [OR = 1.87, 95% CI: (1.12-3.10)], hypertension [OR = 1.27, 95% CI: (1.07-1.50)], steroid use [OR = 1.63, 95% CI: (1.41, 1.88)], high white blood cells counts [MD = 0.32, 95% CI: (0.01, 0.63)], and high fibrinogen levels [MD = 0.19, 95% CI: (0.08, 0.30)].

conclusionThis meta-analysis identified risk factors for postoperational VTE in patients with brain tumor, which can serve as a theoretical foundation for medical staff to manage and treat VTE.

trial registrationCRD42023357459.

Indexed as

Brain NeoplasmsVenous ThromboembolismCraniotomyHumansPostoperative ComplicationsPrevalenceRisk FactorsBrain tumorCraniotomyMeta-analysisRisk factorsVenous thromboembolism

Identifiers

PMID37947983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.