Evidence map›Paper›PMID 37947926›Full record

ReviewArchives of virology2023

Bacteriophages and their derived enzymes as promising alternatives for the treatment of Acinetobacter baumannii infections.

Menglu Wang, Yu Ning, Xin Jiao, Jiayi Liu, Jinjuan Qiao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Menglu Wang *Department of Medical Laboratory, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Yu Ning *Department of Medical Laboratory, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Xin JiaoDepartment of Medical Laboratory, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Jiayi LiuDepartment of Medical Laboratory, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China.
Jinjuan QiaoDepartment of Medical Laboratory, Weifang Medical University, Weifang, 261053, Shandong, People's Republic of China. qiaojj@wfmc.edu.cn.ORCID http://orcid.org/0000-0001-9706-8009
Weifang Medical University · CN

Funding

Department of Health of Shandong Province 2019WS593Natural Science Foundation of Shandong Province ZR2020MH305
6 · The paper itself

Abstract

Nosocomial infections with the opportunistic bacterium Acinetobacter baumannii pose a severe challenge to clinical treatment, which is aggravated by the increasing occurrence of multi-drug resistance, especially resistance to carbapenems. The use of phage therapy as an alternative and supplement to the current antibiotics has become an important research topic in the post-antibiotic era. This review summarizes in vivo and in vitro studies on phage therapy against multi-drug-resistant A. baumannii infection that have used different approaches, including treatment with a single phage, combination with other phages or non-phage agents, and administration of phage-derived enzymes. We also briefly discuss the current challenges of phage-based therapy as well as promising approaches for the treatment of A. baumannii infection in the future.

Indexed as

Acinetobacter baumanniiBacteriophagesAnti-Bacterial AgentsCarbapenemsAnti-Bacterial AgentsCarbapenems

Identifiers

PMID37947926
OpenAlexW4388572577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.