Evidence map›Paper›PMID 37947923›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2023

Risk factors for inguinal hernia repair among US adults.

B Cowan, M Kvale, J Yin, S Patel, E Jorgenson, R Mostaedi, H Choquet

Open access · hybridAbstract read
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Visceral Fat Volume and Inguinal Hernia After Robot-Assisted Radical Prostatectomy: A Three-Dimensional CT Analysis.International journal of urology : official journal of the Japanese Urological Association · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Groin hernia.Nature reviews. Disease primers · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Association between constipation and inguinal hernia: a case-control study in an adult population.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2025
    Observational
  15. Obesity and abdominal hernia in ambulatory patients, 2018-2023.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
  16. Obesity and abdominal hernia in ambulatory patients, 2018-2023.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

B CowanUCSF-East Bay General Surgery, Oakland, CA, USA.ORCID http://orcid.org/0000-0001-5885-391X
M KvaleInstitute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-0984-4878
J YinDivision of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, USA.ORCID http://orcid.org/0000-0002-4990-0777
S PatelUCSF-East Bay General Surgery, Oakland, CA, USA.
E JorgensonRegeneron Genetics Center, Tarrytown, NY, USA.ORCID http://orcid.org/0000-0002-5829-8191
R MostaediKPNC, Richmond Medical Center, Richmond, CA, USA.
H ChoquetDivision of Research, Kaiser Permanente Northern California (KPNC), Oakland, CA, USA. helene.choquet@kp.org.ORCID http://orcid.org/0000-0001-9839-8667
Kaiser Permanente · USCalifornia State University, East Bay · USRegeneron (United States) · US

Funding

Genetic Etiology of Abdominal Hernia SusceptibilityR01DK116738 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI AHITUV, NADAV, CHOQUET, HELENE · 2018 to 2020
$1.8M
NIDDK NIH HHS R01 DK116738NIDDK NIH HHS R01DK116738
6 · The paper itself

Abstract

purposeTo investigate demographic, clinical, and behavioral risk factors for undergoing inguinal hernia repair within a large and ethnically diverse cohort.

methodsWe conducted a retrospective case-control study from 2007 to 2020 on 302,532 US individuals from a large, integrated healthcare delivery system with electronic health records, who participated in a survey of determinants of health. Participants without diagnosis or procedure record of an inguinal hernia at enrollment were included. We then assessed whether demographic (age, sex, race/ethnicity), clinical, and behavioral factors (obesity status, alcohol use, cigarette smoking and physical activity) were predictors of undergoing inguinal hernia repair using survival analyses. Risk factors showing statistical significance (P < 0.05) in the univariate models were added to a multivariate model.

resultsWe identified 7314 patients who underwent inguinal hernia repair over the study period, with a higher incidence in men (6.31%) compared to women (0.53%). In a multivariate model, a higher incidence of inguinal hernia repair was associated with non-Hispanic white race/ethnicity, older age, male sex (aHR = 13.55 [95% confidence interval 12.70-14.50]), and more vigorous physical activity (aHR = 1.24 [0.045]), and alcohol drinker status (aHR = 1.05 [1.00-1.11]); while African-American (aHR = 0.69 [0.59-0.79]), Hispanic/Latino (aHR = 0.84 [0.75-0.91]), and Asian (aHR = 0.35 [0.31-0.39]) race/ethnicity, obesity (aHR = 0.33 [0.31-0.36]) and overweight (aHR = 0.71 [0.67-0.75]) were associated with a lower incidence. The use of cigarette was significantly associated with a higher incidence of inguinal hernia repair in women (aHR 1.23 [1.09-1.40]), but not in men (aHR 0.96 [0.91-1.02]).

conclusionInguinal hernia repair is positively associated with non-Hispanic white race/ethnicity, older age, male sex, increased physical activity, alcohol consumption and tobacco use (only in women); while negatively associated with obesity and overweight status. Findings from this large and ethnically diverse study may support future prediction tools to identify patients at high risk of this surgery.

Indexed as

Hernia, InguinalAdultCase-Control StudiesFemaleHerniorrhaphyHumansMaleObesityOverweightRetrospective StudiesRisk FactorsEpidemiology of inguinal herniaHernia repairInguinal herniaInguinal hernia risk factors

Identifiers

PMID37947923
PMCPMC10700424
OpenAlexW4388567702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.