Evidence map›Paper›PMID 37947660›Full record

ArticleCells2023

Nathalia L M Lara, Taylor Goldsmith, Paula Rodriguez-Villamil, Felipe Ongaratto, Staci Solin, Dennis Webster, Uyanga Ganbaatar, Shane Hodgson, Stanislas M A S Corbière, Alla Bondareva and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Male germ cell technologies in large animals.The Journal of reproduction and development · 2026
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Nathalia L M LaraFaculty of Veterinary Medicine, University of Calgary, Calgary, AB T2N4N1, Canada.ORCID 0000-0002-8170-6384
Taylor GoldsmithRecombinetics, Inc., St. Paul, MN 55121, USA.
Paula Rodriguez-VillamilRecombinetics, Inc., St. Paul, MN 55121, USA.
Felipe OngarattoRecombinetics, Inc., St. Paul, MN 55121, USA.
Staci SolinRecombinetics, Inc., St. Paul, MN 55121, USA.
Dennis WebsterRecombinetics, Inc., St. Paul, MN 55121, USA.
Uyanga GanbaatarRecombinetics, Inc., St. Paul, MN 55121, USA.
Shane HodgsonRecombinetics, Inc., St. Paul, MN 55121, USA.
Stanislas M A S CorbièreRecombinetics, Inc., St. Paul, MN 55121, USA.ORCID 0000-0001-9329-712X
Alla BondarevaFaculty of Veterinary Medicine, University of Calgary, Calgary, AB T2N4N1, Canada.
Daniel F CarlsonRecombinetics, Inc., St. Paul, MN 55121, USA.
Ina DobrinskiFaculty of Veterinary Medicine, University of Calgary, Calgary, AB T2N4N1, Canada.ORCID 0000-0002-0695-2606
Recombinetics (United States) · USUniversity of Calgary · CA

Funding

Transplantation of Testis Stem Cells in Large AnimalsR01OD016575 · OD · UNIVERSITY OF CALGARY · PI DOBRINSKI, INA · 2013 to 2024
$2.4M
Modeling Disease in Swine by Transplantation of Gene Targeted Germ CellsR44GM108150 · NIGMS · RECOMBINETICS, INC. · PI CARLSON, DANIEL FRED · 2018 to 2019
$2.0M
NIGMS NIH HHS R44 GM108150NIH HHS R01 OD016575NIH HHS R01OD016575NIH HHS R44GM108150
6 · The paper itself

Abstract

Spermatogonial stem cell (SSC) transplantation into the testis of a germ cell (GC)-depleted surrogate allows transmission of donor genotype via donor-derived sperm produced by the recipient. Transplantation of gene-edited SSCs provides an approach to propagate gene-edited large animal models. DAZL is a conserved RNA-binding protein important for GC development, and

Indexed as

SemenSpermatogoniaAnimalsMaleSpermatozoaStem Cell TransplantationSwineTestisDAZLDAZL knockoutgenetically modified pigsspermatogonial stem cell transplantation

Identifiers

PMID37947660
PMCPMC10649044
OpenAlexW4388424101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.