ArticleJornal brasileiro de nefrologia
Renal osteodystrophy and clinical outcomes: a prospective cohort study.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Burden of Secondary Hyperparathyroidism Among Patients on Hemodialysis: A Cross-Sectional Study.Cureus · 2025Article
- Bone aluminum accumulation in the current era.Jornal brasileiro de nefrologia · 2024Article
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Authors and funding
9 authors.
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Abstract
introductionRenal osteodystrophy (ROD) refers to a group of bone morphological patterns that derive from distinct pathophysiological mechanisms. Whether the ROD subtypes influence long-term outcomes is unknown. Our objective was to explore the relationship between ROD and clinical outcomes.
methodsThis study is a subanalysis of the Brazilian Registry of Bone Biopsies (REBRABO). Samples from individual patients were classified as having osteitis fibrosa (OF), mixed uremic osteodystrophy (MUO), adynamic bone disease (ABD), osteomalacia (OM), normal/minor alterations, and according to turnover/mineralization/volume (TMV) system. Patients were followed for 3.4 yrs. Clinical outcomes were: bone fractures, hospitalization, major adverse cardiovascular events (MACE), and death.
resultsWe enrolled 275 participants, of which 248 (90%) were on dialysis. At follow-up, 28 bone fractures, 97 hospitalizations, 44 MACE, and 70 deaths were recorded. ROD subtypes were not related to outcomes.
conclusionThe incidence of clinical outcomes did not differ between the types of ROD.
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