Evidence map›Paper›PMID 37947336›Full record

ArticleJournal of the National Cancer Institute. Monographs2023

Opportunities, challenges, and future directions for simulation modeling the effects of structural racism on cancer mortality in the United States: a scoping review.

Jinani Jayasekera, Safa El Kefi, Jessica R Fernandez, Kaitlyn M Wojcik, Jennifer M P Woo, Adaora Ezeani, Jennifer L Ish, Manami Bhattacharya, Kemi Ogunsina, Che-Jung Chang and 13 more

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the National Cancer Institute. Monographs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Factors Associated with Head and Neck Cancer Postoperative Radiotherapy Delays: A Systematic Review and Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Assessing Upstream Structural and Social Drivers of Health in Breast Cancer Survivorship: The Pathways Study Neighborhood Resource.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Racial, Ethnic, and Socioeconomic Disparities in Meeting Physical Activity Guidelines among Female Breast Cancer Survivors in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  10. Article
  11. Population simulation modeling of disparities in US breast cancer mortality.Journal of the National Cancer Institute. Monographs · 2023
    Article
  12. Article
  13. Data gaps and opportunities for modeling cancer health equity.Journal of the National Cancer Institute. Monographs · 2023
    Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jinani JayasekeraDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-9212-7225
Safa El KefiNYU Langone Health, New York University, New York, NY, USA.
Jessica R FernandezDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Kaitlyn M WojcikDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Jennifer M P WooEpidemiology Branch at the National Institute of Environmental Health Sciences at the National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-8455-3996
Adaora EzeaniHealth Behaviors Research Branch of the Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA.ORCID 0000-0002-1395-7894
Jennifer L IshEpidemiology Branch at the National Institute of Environmental Health Sciences at the National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-8618-9494
Manami BhattacharyaCancer Prevention Fellowship Program, Division of Cancer Prevention, and the Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA.ORCID 0000-0003-3116-6065
Kemi OgunsinaEpidemiology Branch at the National Institute of Environmental Health Sciences at the National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1616-0944
Che-Jung ChangEpidemiology Branch at the National Institute of Environmental Health Sciences at the National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0352-7572
Camryn M CohenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.ORCID 0000-0002-7412-9910
Stephanie PonceDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Dalya KamilDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Julia ZhangDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Randy LeDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.
Amrita L RamanathanDiabetes, Endocrinology, & Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
Gisela ButeraOffice of Research Services, National Institutes of Health Library, Bethesda, MD, USA.ORCID 0000-0003-3976-0018
Christina ChapmanDepartment of Radiation Oncology, Baylor College of Medicine, and the Center for Innovations in Quality, Effectiveness, and Safety in the Department of Medicine, Baylor College of Medicine and the Houston Veterans Affairs, Houston, TX, USA.ORCID 0000-0002-8513-5398
Shakira J GrantDepartment of Medicine, Division of Hematology, University of North Carolina, Chapel Hill, NC, USA.
Marquita W Lewis-ThamesDepartment of Medical Social Science, Center for Community Health at Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0001-5909-7167
Chiranjeev DashOffice of Minority Health and Health Disparities Research at the Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC, USA.ORCID 0000-0002-3314-8461
Traci N BetheaOffice of Minority Health and Health Disparities Research at the Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC, USA.ORCID 0000-0003-3205-2078
Allana T FordeDivision of Intramural Research at the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-3097-0038

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Comparative Modeling of Precision Breast Cancer Control Across the Translational Continuum - SupplementU01CA253911 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI ALAGOZ, OGUZHAN, DE KONING, HARRY J · 2020 to 2025
$10.6M
UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
Comparative Modeling: Informing Breast Cancer Control Practice and PolicyU01CA199218 · NCI · GEORGETOWN UNIVERSITY · PI BERRY, DONALD A, DE KONING, HARRY J · 2015 to 2019
$9.0M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MOHR, DAVID CURTIS · 2020 to 2024
$7.1M
Improving adherence to posttreatment follow-up care for rural lung cancer survivors through a community-clinical survivorship care team modelK01CA262342 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEWIS, MARQUITA W. · 2021 to 2025
$801k
An assessment of whether aspirin and/or vitamin D improves breast cancer outcomes in Black women and the modifying effect of genetic variantsK01CA212056 · NCI · GEORGETOWN UNIVERSITY · PI BETHEA, TRACI N. · 2017 to 2021
$656k
Functional Trajectories and Illness Experiences of Older Adults with Multiple MyelomaR03AG074030 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GRANT, SHAKIRA JEANENE · 2021 to 2022
$311k
NCATS NIH HHS UL1 TR001422NCI NIH HHS K01 CA212056NCI NIH HHS K01CA212056NCI NIH HHS K01 CA262342NCI NIH HHS K01CA262342NCI NIH HHS K12 CA120780NCI NIH HHS U01 CA199218NCI NIH HHS U01 CA253911NIA NIH HHS P30 AG059988NIA NIH HHS R03 AG074030NIEHS NIH HHS
6 · The paper itself

Abstract

purposeStructural racism could contribute to racial and ethnic disparities in cancer mortality via its broad effects on housing, economic opportunities, and health care. However, there has been limited focus on incorporating structural racism into simulation models designed to identify practice and policy strategies to support health equity. We reviewed studies evaluating structural racism and cancer mortality disparities to highlight opportunities, challenges, and future directions to capture this broad concept in simulation modeling research.

methodsWe used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review Extension guidelines. Articles published between 2018 and 2023 were searched including terms related to race, ethnicity, cancer-specific and all-cause mortality, and structural racism. We included studies evaluating the effects of structural racism on racial and ethnic disparities in cancer mortality in the United States.

resultsA total of 8345 articles were identified, and 183 articles were included. Studies used different measures, data sources, and methods. For example, in 20 studies, racial residential segregation, one component of structural racism, was measured by indices of dissimilarity, concentration at the extremes, redlining, or isolation. Data sources included cancer registries, claims, or institutional data linked to area-level metrics from the US census or historical mortgage data. Segregation was associated with worse survival. Nine studies were location specific, and the segregation measures were developed for Black, Hispanic, and White residents.

conclusionsA range of measures and data sources are available to capture the effects of structural racism. We provide a set of recommendations for best practices for modelers to consider when incorporating the effects of structural racism into simulation models.

Indexed as

NeoplasmsSystemic RacismBlack or African AmericanHealth Status DisparitiesHispanic or LatinoHumansUnited StatesWhite

Identifiers

PMID37947336
PMCPMC10637025

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.