SynthesisSports health
Acute and Chronic Effects of Blood Flow Restriction Training in Physically Active Patients With Anterior Cruciate Ligament Reconstruction: A Systematic Review.
Synthesis in Sports health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Effects of blood-flow restriction training on dynamic postural control and ankle function in individuals with chronic ankle instability: a systematic review and meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2026Pooled it
- Effects of exercise therapy on dynamic posture control and self-report function in individuals with chronic ankle instability: a systematic review with pairwise and network meta-analysis.EFORT open reviews · 2026Pooled it
- Blood flow restriction training for lower limb injury prevention and rehabilitation in dancers: a scoping review of current evidence and future directions.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Summary of the best evidence on blood flow restriction training for patients after anterior cruciate ligament reconstruction surgery.Frontiers in rehabilitation sciences · 2026Pooled it
- Blood Flow Restriction Training in Knee Arthroplasty: A Systematic Review of Current Evidence on Postoperative Muscle Strength and Function.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Effect and Mechanism of a New Method of Low-Intensity Resistance Training Combined with Blood Flow Restriction on Sports Biomechanics of Young People.Journal of sports science & medicine · 2025Trial
- Blood Flow Restriction Training After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2026Review
- ACL rehabilitation after reconstruction: Evidence-based consensus recommendations from the German Knee Society-Part IV.Journal of experimental orthopaedics · 2026Article
- Optimizing return to sports after anterior cruciate ligament reconstruction: A multi-factorial umbrella review on rehabilitation strategies.Journal of clinical orthopaedics and trauma · 2025Review
- From Past to Future: Emergent Concepts of Anterior Cruciate Ligament Surgery and Rehabilitation.Journal of clinical medicine · 2025Review
- Blood flow restriction-enhanced platelet-rich plasma: A pilot randomised controlled trial protocol.Journal of experimental orthopaedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextMuscle atrophy and loss of knee function are common findings after anterior cruciate ligament (ACL) reconstruction. Rehabilitation through blood flow restriction (BFR) has gained clinical relevance when combined with low loads to improve these disorders in recent years.
objectiveTo evaluate the rehabilitation effectiveness of ACL reconstruction with the use of BFR on pain, functionality, strength, and muscle mass in physically active people. DATA SOURCES: A search of PubMed, Web of Science, and MEDLINE was performed on March 31, 2023, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. STUDY SELECTION: Randomized clinical trials with active adults who underwent ACL surgery were included. They had to compare conventional treatments with the use of BFR, reporting values of pain, functionality, strength, or cross-sectional area (CSA). Articles whose participants presented concomitant injuries and whose intervention combined the use of BFR with treatments other than resistance training were excluded. STUDY
designSystematic review. LEVEL OF EVIDENCE: Level 2. DATA EXTRACTION: Study design, population, cuff pressure, and main outcomes including strength, quadriceps CSA, pain, and functionality.
resultsSix studies out of a total of 389 were included (152 participants; 90 men and 62 women). These included studies showed no differences on CSA or strength when comparing BFR training with high loads exercise. BFR has demonstrated improvements in knee functionality and pain compared with other interventions such as immobilization or high loads training.
conclusionThe use of low loads combined with BFR improves pain, strength, functionality, and CSA. In addition, knee pain reduction and functionality are greater with BFR compared with the use of high loads or immobilization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.