Evidence map›Paper›PMID 37946482›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2023

Bo's abdominal acupuncture improves disordered metabolism in obese type 2 diabetic rats through regulating fibroblast growth factor 21 and its related adipokines.

Qin Xihui, Pang Jianli, Xiong Guan, Feng Jie

Open access · greenAbstract read
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Qin XihuiSchool of Pharmaceutical Sciences, Guangxi Medical University, Nanning 530021, China.
Pang JianliDepartment of Endocrinology, Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine, Nanning 530011, China.
Xiong GuanDepartment of Gynecology and obstetrics, the Eighth People's Hospital of Nanning, Nanning 530007, China.
Feng JieSchool of Pharmaceutical Sciences, Guangxi Medical University, Nanning 530021, China.
Guangxi Medical University · CN

Funding

National Natural Science Foundation of China 81560731
6 · The paper itself

Abstract

objectiveTo investigate the effect of Bo's abdominal acupuncture (BOAA) on fibroblast growth factor 21 (FGF21) and its related adipokines in type 2 diabetes mellitus (T2DM) rats.

methodsThis study established obese T2DM rat model by high-fat diet (HFD) with a dose of streptozotocin (STZ, 30 mg/kg). Obese T2DM rats were randomly subdivided into four groups (

resultsTreatment with BOAA attenuated the histopathological changes in visceral fat and restored the alterations in the levels of body weight, fasting blood glucose (FBG), homeostasis model assessment for insulin resistance (HOMA-IR). BOAA treatment significantly decreased the levels of triglyceride, total cholesterol, low density lipoprotein cholesterol, leptin, and increased the serum levels of high-density lipoprotein cholesterol, fibroblast growth factor 21 (FGF21), adiponectin (ADP), peroxisome proliferator-activated receptor γ (PPAR-γ), C-peptide (C-P) in obese T2DM rats. Furthermore, BOAA treatment significantly increased the mRNA expressions of FGF21, ADP, leptin, PPAR-γ, PPAR-α and adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK). Besides, BOAA treatment upregulated the protein expressions of fibroblast growth factor receptors3 (FGFR3), PPAR-

conclusionsBOAA treatment reduced FBG and body weight, and improved insulin sensitivity through regulating FGF21 signaling pathway and its related adipokine in obese T2DM rats.

Indexed as

Acupuncture TherapyDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Insulin ResistanceAdipokinesAMP-Activated Protein KinasesAnimalsBody WeightCholesterolDiet, High-FatFibroblast Growth FactorsLeptinObesityPeroxisome Proliferator-Activated ReceptorsRatsAdipokinesAMP-Activated Protein KinasesCholesterolfibroblast growth factor 21Fibroblast Growth FactorsLeptinPeroxisome Proliferator-Activated ReceptorsadipokinesBo's abdominal acupuncturediabetes mellitus, type 2fibroblast growth factorsinsulin resistanceobesity

Identifiers

PMID37946482
PMCPMC10623386
OpenAlexW4388578464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.