ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2023
Dangua Fang regulating tricarboxylic acid cycle and respiratory chain and its mechanism in diabetic rats.
Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Clinical observation of white eye distribution in patients with hyperlipidemia: an artificial intelligence digital visual examination technique.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2025Article
- Dangua Fang induces anti-glucolipid metabolism disorder effects similar to those of direct NFIL3 inhibition.Frontiers in microbiology · 2025Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the influence and possible targets of Dangua Fang on tricarboxylic acid (TCA) cycle and respiratory chain to enrich the prescription's mechanism of effective intervention on glycolipid metabolic diseases such as type 2 diabetes.
methodsAfter interventional rats were fed with high glucose and high fat diet ad libitum for 4 weeks, intraperitoneally injected streptozotocin to induce diabetic model. According to blood glucose level,28 diabetic rats were selected and continued to be fed with high glucose and high fat diet, were stratified by body weight, and divided randomly by blood glucose into Model group (was given sterile water by gastric perfusion and injected aquae pro injection intraperitoneally), Dangua group [Dangua liquor 20.5 g·kg
resultsThe levels of BW, ICA, α-KG and Nampt-mRNA in the Model group are lower than that in the Normal group (
conclusionDangua Fang increases the metabolic flux of TCA cycle and optimizes respiratory chain function by up-regulating Nampt expression.
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