Evidence map›Paper›PMID 37946414›Full record

ArticleAnimal bioscience2024

Multiomics analyses of Jining Grey goat and Boer goat reveal genomic regions associated with fatty acid and amino acid metabolism and muscle development.

Zhaohua Liu, Xiuwen Tan, Qing Jin, Wangtao Zhan, Gang Liu, Xukui Cui, Jianying Wang, Xianfeng Meng, Rongsheng Zhu, Ke Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal bioscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  14. The Effects of Composite Alkali-Stored SpentAnimals : an open access journal from MDPI · 2024
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Zhaohua LiuInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Xiuwen TanInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Qing JinInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Wangtao ZhanShandong Animal Husbandry General Station, Jinan 250100, China.
Gang LiuShandong Animal Husbandry General Station, Jinan 250100, China.
Xukui CuiInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Jianying WangInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Xianfeng MengInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Rongsheng ZhuInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Ke WangInstitute of Animal Science and Veterinary Medicine, Shandong Key Lab of Animal Disease Control and Breeding, Shandong Academy of Agricultural Sciences, Jinan 250100, China.

Funding

Agricultural Variety Improvement Project of Shandong Province 2021LZGC010Ministry of Agriculture and Rural AffairsMinistry of FinanceNatural Science Foundation of Shandong Province ZR2022MC077Shandong Academy of Agricultural Sciences CXGC2023A33Shandong Provincial Sheep and Goat Industry Technology System SDAIT-10-02
6 · The paper itself

Abstract

objectiveJining Grey goat is a local Chinese goat breed that is well known for its high fertility and excellent meat quality but shows low meat production performance. Numerous studies have focused on revealing the genetic mechanism of its high fertility, but its highlighting meat quality and muscle growth mechanism still need to be studied.

methodsIn this research, an integrative analysis of the genomics and transcriptomics of Jining Grey goats compared with Boer goats was performed to identify candidate genes and pathways related to the mechanisms of meat quality and muscle development.

resultsOur results overlap among five genes (ABHD2, FN1, PGM2L1, PRKAG3, RAVER2) and detected a set of candidate genes associated with fatty acid metabolism (PRKAG3, HADHB, FASN, ACADM), amino acid metabolism (KMT2C, PLOD3, NSD2, SETDB1, STT3B, MAN1A2, BCKDHB, NAT8L, P4HA3) and muscle development (MSTN, PPARGC1A, ANKRD2). Several pathways have also been detected, such as the FoxO signaling pathway and Apelin signaling pathway that play roles in lipid metabolism, lysine degradation, N-glycan biosynthesis, valine, leucine and isoleucine degradation that involving with amino acid metabolism.

conclusionThe comparative genomic and transcriptomic analysis of Jining Grey goat and Boer goat revealed the mechanisms underlying the meat quality and meat productive performance of goats. These results provide valuable information for future breeding of goats.

Indexed as

GoatMeat QualityMuscle DevelopmentRNA-seqSelective Signature

Identifiers

PMID37946414
PMCPMC11065957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.