Evidence map›Paper›PMID 37946273›Full record

ArticleJournal of medical case reports2023

Magnetic resonance imaging and next-generation sequencing for the diagnosis of cystic echinococcosis in the intradural spine: a case report.

Xiaojie Lao, Diefei Hu, Lei Ji, Tingzheng Zhan, Tiantian Li, Shuming Luo, Xianli Xu, Chunlan Zhang, Maowei Chen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xiaojie Lao *Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, China.
Diefei Hu *Department of Infectious Diseases, Guangxi Medical University First Affiliated Hospital, Nanning, China.
Lei JiDepartment of Infectious Diseases, Wuming Hospital of Guangxi Medical University, Nanning, China.
Tingzheng ZhanDepartment of Parasitology, Guangxi Medical University, Nanning, Guangxi, China.
Tiantian LiDepartment of Infectious Diseases, Wuming Hospital of Guangxi Medical University, Nanning, China.
Shuming LuoDepartment of Infectious Diseases, Guangxi Medical University First Affiliated Hospital, Nanning, China.
Xianli XuDepartment of Infectious Diseases, Wuming Hospital of Guangxi Medical University, Nanning, China.
Chunlan ZhangDepartment of Infectious Diseases, Wuming Hospital of Guangxi Medical University, Nanning, China.
Maowei ChenDepartment of Infectious Diseases, Wuming Hospital of Guangxi Medical University, Nanning, China. chenmaowei2008@163.com.
Guangxi Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CNBeijing Ditan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCystic echinococcosis (CE) is a parasitic zoonotic disease caused by the larval stage of Echinococcus granulosus. The liver and lungs are the most common sites for infection. Infection of the intradural spine is rare. CASE PRESENTATION: A 45-year-old woman of Han ethnicity presented with a chronic history of recurrent lumbar pain. Magnetic resonance imaging of the lumbar spine revealed the classical characteristic of multiple cystic lesions of variable sizes, manifesting a "bunch of grapes" appearance, localized within the spinal canal at the L4-L5 vertebral level. In the meanwhile, metagenomic next-generation sequencing identified Echinococcosis granulosa. The patient underwent surgery to remove the cyst entirely and subsequently took albendazole 400 mg orally twice daily for 6 months.

conclusionSpinal CE should be suspected in patients with multiple spinal cystic lesions and zoonotic exposure. metagenomic next-generation sequencing serves as a robust diagnostic tool for atypical pathogens, particularly when conventional tests are inconclusive. Prompt and aggressive treatment for spinal cystic echinococcosis is imperative, and further research is warranted for improved diagnostic and therapeutic strategies.

Indexed as

EchinococcosisFemaleHigh-Throughput Nucleotide SequencingHumansLumbar VertebraeMagnetic Resonance ImagingMiddle AgedCase reportCystic echinococcosisHydatid diseaseNext-generation sequencing

Identifiers

PMID37946273
PMCPMC10636940
OpenAlexW4388551815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.