SynthesisBMC public health2023
What works in interventions targeting loneliness: a systematic review of intervention characteristics.
Synthesis in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Systematic Review of Loneliness and Social Isolation Interventions in Obesity and Obesity-Related Complications.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Interventions against loneliness and social isolation in older adults- a systematic review.BMC public health · 2026Pooled it
- Efficacy of Technology-Based Interventions on the Reduction of Loneliness: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Loneliness without an epidemic: gendered pathways, health consequences, and intervention gaps among men in the United States.Frontiers in public health · 2026Pooled it
- Pooled it
- [Internet-based self-help for loneliness-a systematic review].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024Pooled it
- Efficacy of relational agents for loneliness across age groups: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Social Isolation, Loneliness, and Cardiovascular Mortality: The Role of Health Care System Interventions.Current cardiology reports · 2024Pooled it
- Article
- Social inclusion of people with severe mental illness: a review of current practices, evidence and unmet needs, and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Experiences of loneliness among people with a diagnosis of 'personality disorder': A qualitative interview study in the UK.PLOS mental health · 2026Article
- All the Lonely People: An Integrated Review and Research Agenda on Work and Loneliness.Journal of management · 2026Review
- Loneliness as a sex-specific risk factor for cognitive aging.Frontiers in human neuroscience · 2026Review
- Mapping loneliness prevention and alleviation interventions: a comparative survey of Basel, Bern, Zurich, and Dublin.Frontiers in public health · 2026Article
- Loneliness in schizophrenia: Just loneliness.Annals of the New York Academy of Sciences · 2025Review
- Digital bridges to social connection: A systematic review and meta-analysis of digital interventions for loneliness and social isolation.Internet interventions · 2025Review
- Targeting childhood loneliness in china: in silico interventions and moderated network analysis.Child and adolescent psychiatry and mental health · 2025Article
- The relationship between state-fear of missing out, loneliness, adaptive perfectionism and social media use in university students: a questionnaire and intervention study.BMC psychology · 2025Article
- Loneliness among family medicine providers and its impact on clinical and teaching practice.Scientific reports · 2025Article
- Loneliness among older adults in Europe: time to integrate health and social care.Internal and emergency medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLoneliness has been linked to negative health and economic outcomes across the life course. Health effects span both physical and mental health outcomes, including negative health behaviours, lower well-being, and increased mortality. Loneliness is however preventable with effective intervention. This systematic review aims to identify what has worked in interventions for loneliness to guide the development of future interventions.
methodsEight electronic databases (Medline, Embase, PsycINFO, Social Policy and Practice, Social Sciences Citation Index, Epistemonikos, CINAHL, Cochrane Library) were systematically searched from inception to February 2022 using terms for intervention and loneliness to identify relevant interventions in the general population. No restrictions on age, socio-economic status, or geographic location were imposed. Studies were to measure loneliness as the primary outcome through a validated scale or single-item question. Case studies were excluded. Additional studies were identified through citation chasing. Extracted data included study and intervention characteristics, and intervention effectiveness for cross-study comparison. Critical appraisal was conducted using the Joanna Briggs Institute and Critical Appraisal Skills Programme tools before the studies were summarised in a narrative synthesis.
resultsSearches identified 4,734 hits, from which 22 studies were included in this review. Of these studies, 14 were effective in reducing loneliness. Additionally, five studies presented unclear findings, and three concluded no decrease in loneliness. Interventions varied between group vs. individual format, online vs. in person delivery, and regarding both intervention duration and individual session length. Furthermore, this review highlighted five key areas when considering designing an intervention for loneliness: use of between session interaction, inclusion of clear learning mechanisms, role of active participation, number of opportunities for group or facilitator interaction, and variation in teaching and learning styles.
conclusionsGroup sessions seem preferred to individual formats, and interaction through active participation and group or facilitator contact appear beneficial, however studies also recognised the importance of a person-tailored approach to delivery. Studies suggest there is no 'quick fix' to loneliness, but that learnt practices, behaviours, and community connection should be built into one's lifestyle to achieve sustained intervention effectiveness. Future interventions should consider longer follow-up periods, male and populations with lower educational levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.