Evidence map›Paper›PMID 37946084›Full record

ArticleNature metabolism2023

Vitamin B

Peter Kreuzaler, Paolo Inglese, Avinash Ghanate, Ersa Gjelaj, Vincen Wu, Yulia Panina, Andres Mendez-Lucas, Catherine MacLachlan, Neill Patani, Catherine B Hubert and 30 more

Open access · hybridAbstract read
In one paragraph

Article in Nature metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 55 citations in OpenAlex.

  1. Targeting MYC-Driven Cancers: From Oncogenic Addiction to Therapeutic Vulnerability.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
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  4. When vitamins decide life or death.Cell death and differentiation · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
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  11. Review
  12. Article
  13. Article
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  15. Review
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  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 6 institutions in 3 countries.

Peter KreuzalerThe Francis Crick Institute, London, UK. peter.kreuzaler@uni-koeln.de.ORCID 0000-0001-8684-9424
Paolo Inglese *Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK.ORCID 0000-0001-6179-9643
Avinash Ghanate *The Francis Crick Institute, London, UK.ORCID 0000-0002-6284-7667
Ersa Gjelaj *The Francis Crick Institute, London, UK.ORCID 0000-0002-5168-3724
Vincen WuFaculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK.
Yulia PaninaThe Francis Crick Institute, London, UK.
Andres Mendez-LucasThe Francis Crick Institute, London, UK.
Catherine MacLachlanThe Francis Crick Institute, London, UK.ORCID 0000-0002-3606-6672
Neill PataniThe Francis Crick Institute, London, UK.
Catherine B HubertThe Francis Crick Institute, London, UK.ORCID 0000-0001-6057-8734
Helen HuangFaculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK.
Gina GreenidgeThe National Physical Laboratory, Teddington, UK.
Oscar M RuedaUniversity of Cambridge, MRC Biostatistics Unit, Cambridge Biomedical Campus, Cambridge, UK.ORCID 0000-0003-0008-4884
Adam J TaylorThe National Physical Laboratory, Teddington, UK.
Evdoxia KaraliSignalling and Cancer Metabolism Team, Division of Cancer Biology, The Institute of Cancer Research, London, UK.ORCID 0000-0002-1196-3553
Emine KazancSignalling and Cancer Metabolism Team, Division of Cancer Biology, The Institute of Cancer Research, London, UK.
Amy SpicerThe Francis Crick Institute, London, UK.ORCID 0000-0001-6474-1498
Alex DexterThe National Physical Laboratory, Teddington, UK.ORCID 0000-0001-8536-4417
Wei LinThe Francis Crick Institute, London, UK.
Daria ThompsonThe Francis Crick Institute, London, UK.
Mariana Silva Dos SantosThe Francis Crick Institute, London, UK.ORCID 0000-0003-2404-8490
Enrica CalvaniThe Francis Crick Institute, London, UK.
Nathalie LegraveThe Francis Crick Institute, London, UK.ORCID 0000-0003-1172-4955
James K EllisThe Francis Crick Institute, London, UK.
Wendy GreenwoodUniversity of Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK.ORCID 0000-0002-2509-8695
Mary GreenThe Francis Crick Institute, London, UK.
Emma NyeThe Francis Crick Institute, London, UK.
Emma StillThe Francis Crick Institute, London, UK.
CRUK Rosetta Grand Challenge Consortium
Simon BarryImaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.ORCID 0000-0002-8511-0588
Richard J A GoodwinImaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, UK.ORCID 0000-0001-5699-8488
Alejandra BrunaModelling of Paediatric Cancer Evolution, Centre for Paediatric Oncology, Experimental Medicine, Centre for Cancer Evolution: Molecular Pathology Division, The Institute of Cancer Research, Belmont, Sutton, London, UK.ORCID 0000-0003-1214-9665
Carlos CaldasUniversity of Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK.ORCID 0000-0003-3547-1489
James MacRaeThe Francis Crick Institute, London, UK.ORCID 0000-0002-1464-8583
Luiz Pedro Sório de CarvalhoThe Francis Crick Institute, London, UK.
George PoulogiannisSignalling and Cancer Metabolism Team, Division of Cancer Biology, The Institute of Cancer Research, London, UK.ORCID 0000-0002-0529-8614
Greg McMahonThe National Physical Laboratory, Teddington, UK.
Zoltan TakatsFaculty of Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK.ORCID 0000-0002-0795-3467
Josephine BunchThe National Physical Laboratory, Teddington, UK.
Mariia YunevaThe Francis Crick Institute, London, UK. Mariia.Yuneva@crick.ac.uk.ORCID 0000-0003-3455-9374
The Francis Crick Institute · GBNational Physical Laboratory · GBImperial College London · GBInstitute of Cancer Research · GBUniversity of Cambridge · GBAstraZeneca (United Kingdom) · GB

Funding

Medical Research Council MC_UU_00002/16Wellcome Trust FC001223
6 · The paper itself

Abstract

Tumors are intrinsically heterogeneous and it is well established that this directs their evolution, hinders their classification and frustrates therapy

Indexed as

Breast NeoplasmsAnimalsFemaleHumansMicePantothenic AcidProto-Oncogene Proteins c-mycTranscription FactorsVitaminsPantothenic AcidProto-Oncogene Proteins c-mycTranscription FactorsVitamins

Identifiers

PMID37946084
PMCPMC10663155
OpenAlexW4388541093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.