ArticleNature immunology2023
Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection.
Open access · greenAbstract read
In one paragraph
Article in Nature immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 29 citations in OpenAlex.
- Interleukin-33 and its receptor: multifaceted roles and emerging therapeutic potential.Nature reviews. Immunology · 2026Review
- Advances in targeting IL-1 family cytokines for the treatment of inflammatory diseases.Nature reviews. Rheumatology · 2026Review
- Mendelian Randomization Analysis of the IL-1 Cytokine Family Proteins Identifies IL1RL1 as a Potential Causal Contributor to Traumatic Brain Injury Prognosis.Neurocritical care · 2026Article
- The Gut-Pancreas Axis in Type 1 Diabetes: Emerging Insights into Microbiota and Immune Interactions.International journal of molecular sciences · 2026Review
- CNS1-dependent regulatory T cells shape recovery from acute lung injury.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Lung adventitial fibroblasts support type 2 Tregs to shape the response to influenza infection.bioRxiv : the preprint server for biology · 2026Article
- CCR8The Journal of allergy and clinical immunology · 2026Article
- S1PR1 signaling biases neutrophils toward long-lived low-inflammatory functional states.bioRxiv : the preprint server for biology · 2026Article
- Article
- Defining nature, responses and drivers of regulatory- and conventional CD4Frontiers in immunology · 2026Article
- Article
- Multi-site cytokine levels are predictive of primary graft dysfunction following lung transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Prior SARS-CoV-2 infection does not increase heat stress during one hour of exercise in a hot and moderately humid environment.European journal of applied physiology · 2025Article
- The Bordetella type III secretion system effector BteA targets host eosinophil-epithelial signaling to promote IL-1Ra expression and persistence.Communications biology · 2025Article
- Lung structural cells are altered by infeluenza virus leading to rapid immune protection following re-challenge.Nature communications · 2025Article
- The immunology of asthma.Nature immunology · 2025Review
- Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33.Cancer cell · 2025Article
- ERS Congress 2024: highlights from the Basic and Translational Sciences Assembly.ERJ open research · 2025Article
- Elevated Levels of IL-1Ra, IL-1β, and Oxidative Stress in COVID-19: Implications for Inflammatory Pathogenesis.Journal of clinical medicine · 2025Article
- Acute Impact of Nonoptimal Ambient Temperatures on Plasma Levels of 3000 Proteins in Chinese Adults.Environmental science & technology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Jason W GriffithCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Lucas D FaustinoCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Victoria I CottrellCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0009-0001-4311-7036
Keshav NepalCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Lida P HaririDivision of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Rebecca Suet-Yan ChiuCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Michael C JonesCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Amélie JuléHarvard Chan Bioinformatics Core, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Cem GabayDivision of Rheumatology, University Hospitals of Geneva and University of Geneva Faculty of Medicine, Geneva, Switzerland.
Andrew D LusterCenter for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. aluster@mgh.harvard.edu.ORCID 0000-0001-9679-7912
Harvard University · USMassachusetts General Hospital · USUniversity of Geneva · CH
Funding
Research Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6MLung-Resident Memory Th2 cells in Asthma - New Therapeutic TargetsR01AI040618 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LUSTER, ANDREW D · 1997 to 2022
$5.6MAllergen-specific lung-resident Tregs in asthma: Targetable suppressors of resident memory Th2 cellsR01AI168131 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ANDREW D LUSTER · 2022 to 2026
$3.0MDistinct Function and Control of Regulatory T Cell Subsets During InfluenzaK08AI125816 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI GRIFFITH, JASON W. · 2017 to 2021
$1.1MInflux Flow CytometerS10OD016372 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI PREFFER, FREDERIC IRA · 2013 to 2013
$600kImageStream X Analyzer 2011S10OD012027 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI PREFFER, FREDERIC IRA · 2012 to 2012
$595kTranslational Immunology Core's FACSAria Cell SorterS10RR023440 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI PREFFER, FREDERIC IRA · 2008 to 2008
$500kDEPARTMENT OF PATHOLOGY LSR2 CYTOMETER: TRANSPLANTATIONS10RR020936 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI PREFFER, FREDERIC IRA · 2005 to 2005
$389kNCRR NIH HHS S10 RR020936NCRR NIH HHS S10 RR023440NHLBI NIH HHS T32 HL116275NIAID NIH HHS K08 AI125816NIAID NIH HHS R01 AI040618NIAID NIH HHS R01 AI168131NIH HHS S10 OD012027NIH HHS S10 OD016372
Abstract
Regulatory T (T
Indexed as
Influenza, HumanT-Lymphocytes, RegulatoryAnimalsHumansImmunity, InnateInterleukin-1Interleukin 1 Receptor Antagonist ProteinInterleukin-1 Receptor-Like 1 ProteinInterleukin-33LymphocytesMiceIl1rn protein, mouseInterleukin-1Interleukin 1 Receptor Antagonist ProteinInterleukin-1 Receptor-Like 1 ProteinInterleukin-33
Identifiers
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.