ArticlePancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2024
Pancreas volumes in pediatric patients following index acute pancreatitis and acute recurrent pancreatitis.
Article in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Characterization of Healthy Pancreas Morphology Throughout Childhood.Clinical anatomy (New York, N.Y.) · 2026Article
- Hepatobiliary and pancreatic findings on magnetic resonance enterography examinations in children with newly diagnosed inflammatory bowel disease.Pediatric radiology · 2026Article
- Lifespan Pancreas Morphology for Control Versus Type 2 Diabetes Using AI on Largescale Clinical Imaging.Clinical anatomy (New York, N.Y.) · 2026Article
- Pediatric pancreas segmentation from MRI scans with deep learning.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2025Article
- Practical approach to quantitative liver and pancreas MRI in children.Pediatric radiology · 2025Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectivesPancreas volume derived from imaging may objectively reveal volume loss relevant to identifying sequelae of acute pancreatitis (AP) and ultimately diagnosing chronic pancreatitis (CP). The purposes of this study were to: (1) quantify pancreas volume by imaging in children with either (a) a single episode of AP or (b) acute recurrent pancreatitis (ARP), and (2) compare these volumes to normative volumes.
methodsThis retrospective study was institutional review board approved. A single observer segmented the pancreas (3D Slicer; slicer.org) on n = 30 CT and MRI exams for 23 children selected from a prospective registry of patients with either an index attack of AP or with ARP after a known index attack date. Patients with CP were excluded. Segmented pancreas volumes were compared to published normal values.
resultsMean pancreas volumes normalized to body surface area (BSA) in the index AP and ARP groups were 38.2 mL/m
conclusionsA significant fraction (40 %) of children with ARP have pancreas volumes <5th percentile for BSA even in the absence of CP. A similar, but not statistically significant, fraction have pancreas volumes <25th percentile after an index attack of AP. Pancreatic parenchymal volume deserves additional investigation as an objective marker of parenchymal damage from acute pancreatitis and of progressive pancreatitis in children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.