Evidence map›Paper›PMID 37945476›Full record

ArticleSurgery2024

Prevalence and risk factors for dysphagia in older adults after thyroid and parathyroid surgery.

Philip K Crepeau, Whitney Sutton, Zeyad Sahli, Tatiana Fedorova, Jonathon O Russell, Martha A Zeiger, Karen Bandeen-Roche, Jeremy D Walston, Lilah F Morris-Wiseman, Aarti Mathur

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. [Multimorbid patients in endocrine surgery].Chirurgie (Heidelberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Philip K CrepeauDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: pcrepea1@jh.edu.
Whitney SuttonDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Zeyad SahliDepartment of Surgery, The University of Virginia Health System, Charlottesville, VA.
Tatiana FedorovaDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Jonathon O RussellDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Martha A ZeigerCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Karen Bandeen-RocheJohns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, MD; Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Jeremy D WalstonJohns Hopkins Older Americans Independence Center and the Center on Aging and Health, Johns Hopkins University, Baltimore, MD; Division of Geriatrics and Gerontology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD.
Lilah F Morris-WisemanDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Aarti MathurDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins University · USNational Institutes of Health · USUniversity of Virginia Health System · US

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Training and Development of Outstanding Surgeon ScientistsZIEBC011992 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ZEIGER, MARTHA · 2020 to 2024
$9.6M
Clinical and Laboratory Research Training for Surgical OncologistsT32CA126607 · NCI · JOHNS HOPKINS UNIVERSITY · PI CAMERON, ANDREW M. · 2008 to 2024
$6.0M
Cognitive Decline and Incident Dementia in Older Patients with Secondary HyperparathyroidismR01AG076834 · NIA · JOHNS HOPKINS UNIVERSITY · PI Aarti Mathur · 2023 to 2026
$3.3M
Association of Fraility with Post thyroidectomy alterations in Voice, Swallowing, and Quality of LifeK23AG053429 · NIA · JOHNS HOPKINS UNIVERSITY · PI MATHUR, AARTI · 2017 to 2022
$1.0M
NCI NIH HHS T32 CA126607NIA NIH HHS K23 AG053429NIA NIH HHS P30 AG021334NIA NIH HHS R01 AG076834
6 · The paper itself

Abstract

backgroundWe aimed to determine the prevalence and risk factors for dysphagia in adults 65 years and older before and after thyroidectomy or parathyroidectomy.

methodsWe performed a longitudinal prospective cohort study of older adults undergoing initial thyroidectomy or parathyroidectomy. We administered the Dysphagia Handicap Index questionnaire preoperatively and 1, 3, and 6 months postoperatively. We compared preoperative and postoperative total and domain-specific scores using paired t tests and identified risk factors for worse postoperative scores using multivariable logistic regression.

resultsOf the 175 patients evaluated, the mean age was 71.1 years (range = 65-94), 73.7% were female, 40.6% underwent thyroidectomy, 57% underwent bilateral procedures, and 21.1% had malignant diagnoses. Preoperative swallowing dysfunction was reported by 77.7%, with the prevalence 22.4% greater in frail than robust patients (P = .013). Compared to preoperative scores, 43.4% and 49.1% had worse scores at 3 and 6 months postoperatively. Mean functional domain scores increased by 62.3% at 3 months postoperatively (P = .007). Preoperative swallowing dysfunction was associated with a 3.07-fold increased likelihood of worse functional scores at 3 months. Whereas frailty was associated with preoperative dysphagia, there was no association between worse postoperative score and age, sex, race, frailty, body mass index, smoking status, gastroesophageal reflux disease, comorbidity index, malignancy, surgical extent, or type of surgery.

conclusionAdults 65 years and older commonly report swallowing impairment preoperatively, which is associated with a 3.07-fold increased likelihood of worsened dysphagia after thyroid and parathyroid surgery that may persist up to 6 months postoperatively.

Indexed as

Deglutition DisordersFrailtyAgedAged, 80 and overFemaleHumansMalePostoperative ComplicationsPrevalenceProspective StudiesRisk FactorsThyroidectomyThyroid Gland

Identifiers

PMID37945476
PMCPMC10841879
OpenAlexW4388491350

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.