ArticleJournal of cardiovascular computed tomography
Coronary artery stenosis quantification in patients with dense calcifications using ultra-high-resolution photon-counting-detector computed tomography.
Article in Journal of cardiovascular computed tomography. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Comparison of photon-counting CT angiography with energy-integrating CT angiography in coronary artery stenosis: a systematic review and meta-analysis.BMC medical imaging · 2025Pooled it
- Photon-counting CT versus energy-integrating detectors for cardiac imaging: a systematic review of evidence from in vivo human studies on image quality and radiation dose.BMC medical imaging · 2025Pooled it
- Feasibility of ultra-low flow rate coronary CT angiography using photon-counting detector CT: a prospective randomized trial.European radiology experimental · 2026Trial
- Deep Learning-based Monoenergetic Imaging for Calcified Coronary Stenosis Assessment at Energy-integrating Detector CT.Radiology. Cardiothoracic imaging · 2026Article
- Diagnostic Performance of Photon-Counting CT Angiography in Vascular Stenosis Assessment: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2026Review
- Comparison of image quality between photon-counting detector CT and energy-integrating detector coronary CT angiography in heart transplant patients.The international journal of cardiovascular imaging · 2026Article
- Ultra-high spatial resolution at photon-counting computed tomography: technical insights and sustainable applications in cardiothoracic imaging.European radiology experimental · 2026Review
- Prospective comparison of ultra-high-resolution photon-counting detector CT coronary angiography versus conventional CT.The British journal of radiology · 2026Article
- High-resolution deep learning reconstruction to improve the accuracy of CT fractional flow reserve.European radiology · 2025Article
- Simultaneous ultra-high resolution multi-energy cardiac imaging in a dual-source photon counting detector CT system.The British journal of radiology · 2025Article
- Bibliometric analysis of CT-based atherosclerosis plaque imaging in coronary artery disease: from "gatekeeper" of invasive angiography to "whistleblower" of high-risk patients.Quantitative imaging in medicine and surgery · 2025Article
- Photon-Counting CT Enhances Diagnostic Accuracy in Stable Coronary Artery Disease: A Comparative Study with Conventional CT.Journal of clinical medicine · 2025Article
- Learned high resolution energy-integrating detector CT angiography: Harnessing the power of ultra-high-resolution photon counting detector CT.Medical physics · 2025Article
- Preserving noise texture through training data curation for deep learning denoising of high-resolution cardiac EID-CT.Medical physics · 2025Article
- Value of Ultrahigh-Resolution Photon-Counting Detector Computed Tomography in Cardiac Imaging.Echocardiography (Mount Kisco, N.Y.) · 2025Review
- Emerging Imaging Techniques for Atherosclerosis in Systemic Immune-Mediated Inflammatory Conditions.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Photon-counting detector computed tomography in cardiac imaging.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Review
- Standardizing technical parameters and terms for abdominopelvic photon-counting CT: laying the groundwork for innovation and evidence sharing.Abdominal radiology (New York) · 2024Review
- Photon-Counting Detector Computed Tomography (PCD-CT): A New Era for Cardiovascular Imaging? Current Status and Future Outlooks.Journal of cardiovascular development and disease · 2024Review
- Learned high-resolution cardiac CT imaging from ultra-high-resolution PCD-CT.Proceedings of SPIE--the International Society for Optical Engineering · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTo quantify differences in coronary artery stenosis severity in patients with calcified lesions between conventional energy-integrating detector (EID) CT and ultra-high-resolution (UHR) photon-counting-detector (PCD) CT.
methodsPatients undergoing clinically indicated coronary CT angiography were prospectively recruited and scanned first on an EID-CT (SOMATOM Force, Siemens Healthineers) and then a PCD-CT (NAEOTOM Alpha, Siemens Healthineers) on the same day. EID-CT was performed with standard mode (192 × 0.6 mm detector collimation) following our clinical protocol. PCD-CT scans were performed under UHR mode (120 × 0.2 mm detector collimation). For each patient, left main, left anterior descending, right coronary artery, and circumflex were reviewed and the most severe stenosis from dense calcification for each coronary was quantified using commercial software. Additionally, each measured stenosis was assigned a severity category based on percent diameter stenosis, and changes in severity category across EID-CT and PCD-CT were assessed.
resultsA total of 23 patients were enrolled, with 34 coronary artery stenoses analyzed. Stenosis was significantly reduced in PCD-CT compared to EID-CT (p < 0.001), resulting in an average of 11% (SD = 11%) reduction in percent diameter stenosis. Among the 34 lesions, 15 changed in stenosis severity category: 3 went from moderate to minimal, 1 from moderate to mild, 9 from mild to minimal, and 2 from minimal to mild with the use of PCD-CT compared to EID-CT.
conclusionUse of UHR PCD-CT decreased percent diameter stenosis by an average of 11% relative to EID-CT, resulting in 13 of 34 stenoses being downgraded in stenosis severity category, potentially sparing patients from unnecessary intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.