Evidence map›Paper›PMID 37945280›Full record

ArticleBMJ case reports2023

Heterotopic bone formation with extramedullary haematopoiesis in a thyroid nodule.

Jesus García, Mauricio Alvarez, Diana Moreno, Bernarda Acosta

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jesus GarcíaEndrocrinology, Hospital Universitario Nacional de Colombia, Bogota, Colombia.
Mauricio AlvarezEndocrinology, Hospital Militar Central, Bogotá, Colombia drmauricioalvareza@gmail.com.
Diana MorenoEndrocrinology, Hospital Universitario Nacional de Colombia, Bogota, Colombia.
Bernarda AcostaEndrocrinology, Hospital Universitario Nacional de Colombia, Bogota, Colombia.
Hospital Universitario Nacional de Colombia · COHospital Militar Central · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of mature bone and bone marrow in the thyroid gland is an exceedingly rare occurrence. Extramedullary haematopoiesis (EMH) and heterotopic bone formation (HBF) should be suspected when cytology of thyroid nodules reveals evidence of megakaryocytes or bone marrow fat, respectively. The cause of these abnormalities has not been fully elucidated, but the role of bone morphogenic factors (BMPs) in their pathogenesis has been suggested. Both EMH and HBF can be seen in both benign and malignant primary thyroid conditions, and although they have not been definitively associated with significant pathology, it is recommended that extension studies be considered in the event of these findings to rule out concomitant haematological conditions.

Indexed as

Hematologic DiseasesHematopoiesis, ExtramedullaryOssification, HeterotopicThyroid NoduleAgedFemaleHumansEndocrine systemEndocrinologyThyroid disease

Identifiers

PMID37945280
PMCPMC10649758
OpenAlexW4388524693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.