Evidence map›Paper›PMID 37944088›Full record

ArticleJCO global oncology2023

Breast Cancer Germline Genetic Counseling and Testing for Populations of African Heritage Globally: A Scoping Review on Research, Practice, and Bioethical Considerations.

Yoshiko Iwai, Kadiata Toumbou, Takondwa Zuze, Jenny S Morgan, Lusayo Simwinga, Sarah T Wright, Yuri Fedoriw, Oluwadamilola T Oladeru, Onyinye D Balogun, Mya L Roberson and 3 more

Open access · goldAbstract readScoping Review
In one paragraph

Article in JCO global oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Yoshiko IwaiUniversity of North Carolina School of Medicine, Chapel Hill, NC.ORCID 0000-0001-9759-384X
Kadiata ToumbouUNC Gillings School of Public Health, Chapel Hill, NC.
Takondwa ZuzeUNC Project-Malawi, Lilongwe, Malawi.ORCID 0000-0003-3780-0207
Jenny S MorganDepartment of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.ORCID 0000-0002-9421-432X
Lusayo SimwingaUNC Project-Malawi, Lilongwe, Malawi.
Sarah T WrightUNC Health Sciences Library, University of North Carolina at Chapel Hill, Chapel Hill, NC.ORCID 0000-0003-2076-8343
Yuri FedoriwDepartment of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.
Oluwadamilola T OladeruDepartment of Radiation Oncology, University of Florida, Gainesville, FL.ORCID 0000-0002-3476-7790
Onyinye D BalogunDepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY.ORCID 0000-0002-3857-2675
Mya L RobersonDepartment of Health Policy, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC.
Olufunmilayo I OlopadeDepartment of Medicine, University of Chicago, Chicago, IL.ORCID 0000-0002-9936-1599
Tamiwe TomokaUNC Project-Malawi, Lilongwe, Malawi.ORCID 0000-0002-5183-8714
Shekinah N C ElmoreDepartment of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC.ORCID 0000-0002-7136-1597
University of North Carolina at Chapel Hill · USCornell University · USUniversity of Chicago · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite the disproportionately high risk of breast cancer among women of African heritage, little is known about the facilitators and barriers to implementing germline genetic testing and counseling (GT/C).

methodsThis scoping review followed guidelines recommended by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews. Published manuscripts from database inception through 2021 were sourced from PubMed, Cumulative Index to Nursing and Allied Health Literature via EBSCO, Embase, Cochrane Library, and Scopus. Search terms were used to retrieve articles addressing (1) African heritage, (2) breast cancer, and (3) GT or GC. The screening involved abstract and title review and full-text review. Data were extracted for all articles meeting the inclusion criteria.

resultsA total of 154 studies were included. Most studies that took place were conducted in the United States (71.4%), and most first authors (76.9%) were from the United States. GT was conducted in 73 (49.7%) studies.

conclusionThere is a growing body of literature on GT/C for breast cancer in women of African heritage. Future studies on GT/C of African populations should consider increased clarity around racial/ethnic categorizations, continued community engagement, and intentional processes for informed consent.

Indexed as

Breast NeoplasmsEthnicityFemaleGenetic CounselingGenetic TestingHumansUnited States

Identifiers

PMID37944088
PMCPMC10645409
OpenAlexW4388521819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.