ArticleProceedings of the National Academy of Sciences of the United States of America2023
Functional aggregation of cell-free proteins enables fungal ice nucleation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 30 citations in OpenAlex.
- Chemical and physical equilibria shape dual ice-nucleation pathways in an organic crystal.Communications chemistry · 2026Article
- Biochemical characterization of a fungal ice nucleation protein from Podila clonocystis.Scientific reports · 2026Article
- A previously unrecognized class of fungal ice-nucleating proteins with bacterial ancestry.Science advances · 2026Article
- BeStSel: analysis site for protein CD spectra-2025 update.Nucleic acids research · 2025Article
- Microfluidics for the biological analysis of atmospheric ice-nucleating particles: Perspectives and challenges.Biomicrofluidics · 2025Review
- High-speed cryo-microscopy reveals that ice-nucleating proteins ofScience advances · 2024Article
- Profile of Valeria P. Molinero.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
Biological ice nucleation plays a key role in the survival of cold-adapted organisms. Several species of bacteria, fungi, and insects produce ice nucleators (INs) that enable ice formation at temperatures above -10 °C. Bacteria and fungi produce particularly potent INs that can promote water crystallization above -5 °C. Bacterial INs consist of extended protein units that aggregate to achieve superior functionality. Despite decades of research, the nature and identity of fungal INs remain elusive. Here, we combine ice nucleation measurements, physicochemical characterization, numerical modeling, and nucleation theory to shed light on the size and nature of the INs from the fungus
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.