ArticleThe British journal of surgery2024
Risk factors for anastomotic leak and postoperative morbidity after right hemicolectomy for colon cancer: results from a prospective, multi-centre, snapshot study in China.
Article in The British journal of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 27 citations in OpenAlex.
- Review
- Postoperative anastomotic leakage after colon cancer surgery may reduce long-term survival.International journal of colorectal disease · 2026Article
- Risk factor analysis and nomogram model development for anastomotic leakage following laparoscopic radical colorectal cancer surgery.World journal of surgical oncology · 2026Article
- Robotic Right Hemicolectomy with Complete Mesocolic Excision and D3 Lymphadenectomy: Perioperative Complications and Oncologic Outcomes.Surgical oncology insight · 2026Article
- An integrated random forest- and LASSO-derived nomogram for predicting postoperative nosocomial infections in colorectal cancer patients.Perioperative medicine (London, England) · 2026Article
- Revealing shared molecular markers and mechanisms in colorectal cancer and COVID-19 through bioinformatics and machine learning.Briefings in bioinformatics · 2026Article
- Clinical study on the efficacy comparison between ileotransverse colon overlap anastomosis and π-shaped anastomosis in laparoscopic radical right hemicolectomy.Frontiers in surgery · 2026Article
- Nutritional risk score drives postoperative morbidity in colorectal cancer: findings from a LASSO-selected multivariable model in 1013 consecutive patients.Frontiers in nutrition · 2026Article
- Microenvironment-Responsive Nanomaterials for Colorectal Anastomotic Healing: A Signal-Threshold-Response Framework for Stage-Adaptive Repair.International journal of nanomedicine · 2026Review
- A landmark-based dynamic prediction model for anastomotic leakage after rectal cancer surgery: integrating perioperative and postoperative trajectories.Frontiers in oncology · 2026Article
- Preoperative magnetic resonance imaging-based radiomics nomogram model for predicting postoperative anastomotic leakage in colorectal cancer.Annals of coloproctology · 2025Article
- Assessment of colonic interposition graft using indocyanine green: expanding fluorescence imaging techniques in gastrointestinal surgery.Journal of surgical case reports · 2025Article
- Risk factors for postoperative anastomotic leakage in obstructive left colonic carcinoma.Updates in surgery · 2025Article
- Building a risk prediction model for anastomotic leakage postoperative low rectal cancer based on Lasso-Logistic regression.BMC gastroenterology · 2025Article
- The role of intraabdominal drain placement in minimal-invasive right hemicolectomy with complete mesocolic excision - a propensity score matched single center analysis.International journal of colorectal disease · 2025Article
- Impact of gut microbiota on colorectal anastomotic healing (Review).Molecular and clinical oncology · 2025Review
- A standardized surgical approach to appendiceal orifice tumors: a case report.Journal of surgical case reports · 2025Article
- Definition and grading of anastomotic leakage following right hemicolectomy.The British journal of surgery · 2024Article
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54 authors at 20 institutions in 2 countries.
Funding
Abstract
backgroundRight hemicolectomy is the standard treatment for right-sided colon cancer. There is variation in the technical aspects of performing right hemicolectomy as well as in short-term outcomes. It is therefore necessary to explore best clinical practice following right hemicolectomy in expert centres.
methodsThis snapshot study of right hemicolectomy for colon cancer in China was a prospective, multicentre cohort study in which 52 tertiary hospitals participated. Eligible patients with stage I-III right-sided colon cancer who underwent elective right hemicolectomy were consecutively enrolled in all centres over 10 months. The primary endpoint was the incidence of postoperative 30-day anastomotic leak.
resultsOf the 1854 patients, 89.9 per cent underwent laparoscopic surgery and 52.3 per cent underwent D3 lymph node dissection. The overall 30-day morbidity and mortality were 11.7 and 0.2 per cent, respectively. The 30-day anastomotic leak rate was 1.4 per cent. In multivariate analysis, ASA grade > II (P < 0.001), intraoperative blood loss > 50 ml (P = 0.044) and D3 lymph node dissection (P = 0.008) were identified as independent risk factors for postoperative morbidity. Extracorporeal side-to-side anastomosis (P = 0.031), intraoperative blood loss > 50 ml (P = 0.004) and neoadjuvant chemotherapy (P = 0.004) were identified as independent risk factors for anastomotic leak.
conclusionIn high-volume expert centres in China, laparoscopic resection with D3 lymph node dissection was performed in most patients with right-sided colon cancer, and overall postoperative morbidity and mortality was low. Further studies are needed to explore the optimal technique for right hemicolectomy in order to improve outcomes further.
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