Evidence map›Paper›PMID 37943599›Full record

ArticleJMIR research protocols2023

Clinical Prediction Models for Hospital-Induced Delirium Using Structured and Unstructured Electronic Health Record Data: Protocol for a Development and Validation Study.

Sarah E Ser, Kristen Shear, Urszula A Snigurska, Mattia Prosperi, Yonghui Wu, Tanja Magoc, Ragnhildur I Bjarnadottir, Robert J Lucero

Abstract read
In one paragraph

Article in JMIR research protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Identifying Candidate Predictors of Hospital-Acquired Pressure Injuries among Adult, Medical-Surgical Patients Using Clinical Expert Knowledge: A Delphi Study.Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sarah E SerDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0009-0002-9496-6991
Kristen ShearDepartment of Family, Community, and Health Systems Science, College of Nursing, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0002-3848-3576
Urszula A SnigurskaDepartment of Family, Community, and Health Systems Science, College of Nursing, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0001-9806-8553
Mattia ProsperiDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0002-9021-5595
Yonghui WuDepartment of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0002-6780-6135
Tanja MagocIntegrated Data Repository Research Services, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0001-8213-2266
Ragnhildur I BjarnadottirDepartment of Family, Community, and Health Systems Science, College of Nursing, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0001-6325-1200
Robert J LuceroDepartment of Family, Community, and Health Systems Science, College of Nursing, University of Florida, Gainesville, FL, United States.ORCID https://orcid.org/0000-0002-8089-466X

Funding

Advancing Interdisciplinary Science of Aging through Identification of Iatrogenic Complications: The UF EHR Clinical Data Infrastructure for Enhanced Patient Safety among the Elderly (UF-ECLIPSE)R33AG062884 · NIA · UNIVERSITY OF FLORIDA · PI INGIBJARGARDOTTIR BJARNADOTTIR, RAGNHILDUR, LUCERO, ROBERT J · 2021 to 2023
$2.1M
Advancing Interdisciplinary Science of Aging through Identification of Iatrogenic Complications: The UF EHR Clinical Data Infrastructure for Enhanced Patient Safety among the Elderly (UF-ECLIPSE)R21AG062884 · NIA · UNIVERSITY OF FLORIDA · PI INGIBJARGARDOTTIR BJARNADOTTIR, RAGNHILDUR, LUCERO, ROBERT J · 2019 to 2020
$415k
NIA NIH HHS R21 AG062884NIA NIH HHS R33 AG062884
6 · The paper itself

Abstract

backgroundHospital-induced delirium is one of the most common and costly iatrogenic conditions, and its incidence is predicted to increase as the population of the United States ages. An academic and clinical interdisciplinary systems approach is needed to reduce the frequency and impact of hospital-induced delirium.

objectiveThe long-term goal of our research is to enhance the safety of hospitalized older adults by reducing iatrogenic conditions through an effective learning health system. In this study, we will develop models for predicting hospital-induced delirium. In order to accomplish this objective, we will create a computable phenotype for our outcome (hospital-induced delirium), design an expert-based traditional logistic regression model, leverage machine learning techniques to generate a model using structured data, and use machine learning and natural language processing to produce an integrated model with components from both structured data and text data.

methodsThis study will explore text-based data, such as nursing notes, to improve the predictive capability of prognostic models for hospital-induced delirium. By using supervised and unsupervised text mining in addition to structured data, we will examine multiple types of information in electronic health record data to predict medical-surgical patient risk of developing delirium. Development and validation will be compliant to the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) statement.

resultsWork on this project will take place through March 2024. For this study, we will use data from approximately 332,230 encounters that occurred between January 2012 to May 2021. Findings from this project will be disseminated at scientific conferences and in peer-reviewed journals.

conclusionsSuccess in this study will yield a durable, high-performing research-data infrastructure that will process, extract, and analyze clinical text data in near real time. This model has the potential to be integrated into the electronic health record and provide point-of-care decision support to prevent harm and improve quality of care. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/48521.

Indexed as

big dataclinical textdata sciencedeliriumfree texthospital acquiredhospital-acquired conditionhospital inducedmachine learningmodelmodelsnatural language processingpredictpredictionpredictiveriskrisk factorsstructuredtext dataunstructured

Identifiers

PMID37943599
PMCPMC10667972

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.