Evidence map›Paper›PMID 37943506›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2024

All-Inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers.

Andrea Barba-Bon, Nadiia I Gumerova, Elias Tanuhadi, Maryam Ashjari, Yao Chen, Annette Rompel, Werner M Nau

Open access · hybridAbstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Intracellular Delivery of Hydrophilic Glycans Using Superchaotropic Clusters.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Article
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  4. Article
  5. Article
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  7. Review
  8. Article
  9. Article
  10. Compression of Molybdenum Blue Polyoxometalate Cluster Rings.Journal of the American Chemical Society · 2025
    Article
  11. Article
  12. A small-molecule carrier for the intracellular delivery of a membrane-impermeable protein with retained bioactivity.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Configurational Isomerism in Bimetallic Decametalates.Materials (Basel, Switzerland) · 2024
    Article
  14. Article
  15. All-Inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers.Advanced materials (Deerfield Beach, Fla.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Andrea Barba-BonSchool of Science, Constructor University, Campus Ring 1, 28759, Bremen, Germany.ORCID https://orcid.org/0000-0003-0712-4869
Nadiia I GumerovaUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Josef-Holaubek-Platz 2, Wien, 1090, Austria.ORCID https://orcid.org/0000-0003-4375-0103
Elias TanuhadiUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Josef-Holaubek-Platz 2, Wien, 1090, Austria.ORCID https://orcid.org/0000-0001-5474-6260
Maryam AshjariSchool of Science, Constructor University, Campus Ring 1, 28759, Bremen, Germany.
Yao ChenSchool of Science, Constructor University, Campus Ring 1, 28759, Bremen, Germany.
Annette RompelUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Josef-Holaubek-Platz 2, Wien, 1090, Austria.ORCID https://orcid.org/0000-0002-5919-0553
Werner M NauSchool of Science, Constructor University, Campus Ring 1, 28759, Bremen, Germany.ORCID https://orcid.org/0000-0002-7654-6232
Constructor University · DEUniversity of Vienna · AT

Funding

Austrian Science Fund P33089Austrian Science Fund P33927Austrian Science Fund FWF P 33089China Scholarship CouncilDeutsche Forschungsgemeinschaft NA-868/14Deutsche Forschungsgemeinschaft NA-868/15Deutsche Forschungsgemeinschaft NA-868/17Universität Wien Uni:docs fellowship
6 · The paper itself

Abstract

Polyoxometalates (POMs) are known antitumoral, antibacterial, antiviral, and anticancer agents and considered as next-generation metallodrugs. Herein, a new biological functionality in neutral physiological media, where selected mixed-metal POMs are sufficiently stable and able to affect membrane transport of impermeable, hydrophilic, and cationic peptides (heptaarginine, heptalysine, protamine, and polyarginine) is reported. The uptake is observed in both, model membranes as well as cells, and attributed to the superchaotropic properties of the polyoxoanions. In view of the structural diversity of POMs these findings pave the way toward their biomedical application in drug delivery or for cell-biological uptake studies with biological effector molecules or staining agents.

Indexed as

Antineoplastic AgentsMetalsAnionsPolyoxometalatesAnionsAntineoplastic AgentsMetalsPolyoxometalateschaotropic carriersdeliveryKeggin anionsmembrane transportPOM stability

Identifiers

PMID37943506
PMCPMC11475408
OpenAlexW4388538569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.