Evidence map›Paper›PMID 37943383›Full record

ArticleDigestive diseases and sciences2024

Etiological Changes and Prognosis of Hospitalized Patients with Acute Pancreatitis Over a 15-Year Period.

Tianming Lai, Jiarong Li, Zhengang Zhou, Jingwen Rao, Yong Zhu, Liang Xia, Yupeng Lei, Xin Huang, Huajing Ke, Yao Wu and 8 more

Registry-linked trialAbstract read
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In one paragraph

Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07720232 (Effect of Bacillus Subtilis and Enterococcus Faecium Combination Therapy Combined With Conventional Lipid-Lowering Treatment on Triglyceride Levels in Patients With Hypertriglyceridemic Acute Pancreatitis), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07720232 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Bacillus Subtilis and Enterococcus Faecium Combination Therapy Combined With Conventional Lipid-Lowering Treatment on Triglyceride Levels in Patients With Hypertriglyceridemic Acute Pancreatitis: A Prospective Randomized Controlled Trial

TypeinterventionalSponsorJianyin ZhouRan2026 to 2029Enrolled180ConditionsHypertriglyceridemic Acute Pancreatitis, Acute Pancreatitis, Hypertriglyceridemia-induced, HyperlipidemiaArmsLive Combined Bacillus subtilis and Enterococcus faecium Enteric-coated Capsules (LCBE), Standard Care (in control arm)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Tianming LaiDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Jiarong LiDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Zhengang ZhouDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Jingwen RaoDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Yong ZhuDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Liang XiaDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Yupeng LeiDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Xin HuangDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Huajing KeDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Yao WuDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Pi LiuDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Hao ZengDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Huifang XiongDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Lingyu LuoDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Youxiang ChenDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Wenhua HeDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China. hewenhua@ncu.edu.cn.ORCID http://orcid.org/0000-0001-5499-1346
Yin ZhuDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Nonghua LuDepartment of Gastroenterology, Digestive Disease Hospital, First Affiliated Hospital of Nanchang University, 17 Yong Wai Zheng Street, 330006, Nanchang, Jiangxi, People's Republic of China.
Nanchang University · CN

Funding

Jiangxi Clinical Research Center for Gastroenterology 20201ZDG02007Jiangxi Province Outstanding Youth Talent Funding Program 20192BCBL23021National Natural Science Foundation of China 81860122The National Key Clinical Specialist Project (2011)872
6 · The paper itself

Abstract

backgroundThe worldwide incidence of acute pancreatitis (AP) is increasing, but the dominant etiology of AP may vary by country. Mixed etiologies are involved in the increase in the number of AP patients.

aimsThis study was to analyze the etiological changes and prognosis of AP patients and explore the prognosis of AP patients with mixed etiologies.

methodsUsing a retrospective analysis method, AP patients hospitalized from January 2007 to December 2021 were selected from a pancreatic center in Nanchang, China. Trends in the main etiologies were analyzed, and the severity and prognosis of different etiologies were compared.

resultsA total of 10,071 patients were included. Cholelithiasis (56.0%), hyperlipidemia (25.3%), and alcohol (6.5%) were the top three etiologies. The proportion of acute biliary pancreatitis (ABP) showed a decreasing trend, while the proportion of hypertriglyceridemic pancreatitis (HTGP) and alcoholic AP showed an increasing trend (all p

conclusionIn the past 15 years, the proportion of ABP has trended downward, while those of HTGP and alcoholic AP have risen. Among patients with mixed etiologies, those with a mixed hypertriglyceridemia-alcoholic etiology had a worse prognosis.

Indexed as

HypertriglyceridemiaPancreatitis, AlcoholicAcute DiseaseHumansPrognosisRetrospective StudiesAcute pancreatitisEtiologyPrognosisSeverityTrend

Identifiers

PMID37943383
OpenAlexW4388527310

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.