ArticleExperimental and therapeutic medicine2023
Comparison between unilateral and bilateral percutaneous kyphoplasty in the treatment of osteoporotic vertebral compression fracture: A meta‑analysis and systematic review.
Article in Experimental and therapeutic medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Transverse process-pedicle versus conventional transpedicular approach in percutaneous kyphoplasty for osteoporotic vertebral compression fractures: a systematic review and pilot meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Pooled it
- Bone cement distribution patterns in vertebral augmentation for osteoporotic vertebral compression fractures: a systematic review.Journal of orthopaedic surgery and research · 2025Pooled it
- Comparison of the efficacy and safety of unilateral and bilateral approach kyphoplasty in the treatment of osteoporotic vertebral compression fractures: A meta-analysis.Joint diseases and related surgery · 2024Pooled it
- Diagnostic decision-making, vertebral augmentation, and osteoporosis therapy in vertebral compression fractures: a narrative review.Asian spine journal · 2026Article
- Comparison of Bilateral and Unilateral Applications of Percutaneous Vertebroplasty and Kyphoplasty Procedures.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Article
- Is P TO P (Pedicle-To-Pedicle) technique superior to bilateral percutaneous vertebral augmentation for thoracic and lumbar osteoporotic vertebral compression fracture? Evidence from a retrospective study.BMC musculoskeletal disorders · 2026Article
- Unilateral extrapedicular vs. bilateral transpedicular percutaneous kyphoplasty in osteoporotic vertebral compression fractures: an exploratory systematic review and meta-analysis.Frontiers in surgery · 2026Review
- Technical Adaptations in Kyphoplasty for T5 Vertebral Collapse With Sharp Kyphotic Angulation.Cureus · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study collected retrospective research data and compared the safety and efficacy of unilateral and bilateral percutaneous puncture kyphoplasty for the treatment of vertebral fractures caused by osteoporosis, to guide the selection of clinical surgical methods. In the present meta-analysis, PubMed, Embase and the Cochrane Library were searched from the establishment of the databases to March 2023. Studies that reported differences in the efficacy and safety between the unilateral and bilateral approaches in the treatment of osteoporotic vertebral compression fractures were included in the analysis. Duplicate published studies, unpublished studies, studies with incomplete data, animal experiments, literature reviews and systematic studies were excluded from the analysis. All data were processed using STATA 15.1 statistical software. The pooled results demonstrated that there were no significant differences between the unilateral and bilateral approaches in the visual analog scores, Oswestry disability index, height restoration rate or incidence of cement leakage. However, the post-kyphotic angle of the unilateral approach was significantly lower than that of the bilateral approach (standardized mean difference, -0.41; 95% confidence interval, -0.68 to -0.14; P=0.003). Furthermore, the pooled results demonstrated that the unilateral approach required less operative time and a lower volume of injected cement, which is safer for elderly patients who are more likely to have underlying diseases.
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