Evidence map›Paper›PMID 37941540›Full record

ReviewVascular health and risk management2023

Relationship Between Hypertension, Antihypertensive Drugs and Sexual Dysfunction in Men and Women: A Literature Review.

Inmaculada Xu Lou, Jiayue Chen, Kamran Ali, Qilan Chen

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Vascular health and risk management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07152847 (Developing a Psychosexual Education App With Artificial Intelligence for National Health Service Patients on a Psychosexual Services Waiting List), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07152847 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Developing a Psychosexual Education App With Artificial Intelligence for National Health Service Patients on a Psychosexual Services Waiting List: A Pilot Pre Test Post Test Study

TypeinterventionalSponsorLondon Metropolitan UniversityRan2026 to 2027Enrolled150ConditionsSexual DysfunctionArmsPsychosexual education app with artificial intelligence
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Impact of Variability in Blood Pressure and Heart Rate on Beta-Blocker Adherence.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Approach to lubricant use for sexual activity.Canadian family physician Medecin de famille canadien
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Inmaculada Xu Lou *Department of Cardiology, International Education College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, People's Republic of China.
Jiayue Chen *Department of Cardiology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, 310025, People's Republic of China.
Kamran Ali *Department of Oncology, The Fourth Affiliated Hospital, International Institutes of Medicine, Zhejiang University School of Medicine, Yiwu, Zhejiang, 322000, People's Republic of China.ORCID 0000-0002-0304-6130
Qilan ChenDepartment of Cardiology, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, 310025, People's Republic of China.
Zhejiang Chinese Medical University · CNHangzhou Hospital of Traditional Chinese Medicine · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sexual dysfunction pertains to any issue that hinders an individual from attaining sexual contentment. This health issue can have a significant impact on the quality of life and psychological health of affected individuals. Sexual dysfunction can generate stress, anxiety, depression, and low self-esteem, which can lead to a reduction in overall life satisfaction and the quality of interpersonal relationships. Sexual dysfunction can manifest as erectile dysfunction in men or lack of sexual desire in women. Although both sexes can experience sexual problems, there are some significant differences in the manifestation of sexual dysfunction between men and women. In men, sexual dysfunction is usually physical and associated with problems such as erectile dysfunction, while in women, sexual dysfunction is usually related to psychological factors. Additionally, there was an association between hypertension and sexual dysfunction in both the sexes. In men, hypertension can cause erection problems, whereas in women, it can cause vaginal dryness and a decrease in sexual desire. Furthermore, antihypertensive drugs can negatively impact sexual function, which can decrease adherence to drug treatment. However, nebivolol, an antihypertensive drug, has beneficial effects on erectile dysfunction in men. This is believed to be because nebivolol improves blood flow to the penis by producing nitric oxide, which can help improve erections.

Indexed as

Erectile DysfunctionHypertensionAntihypertensive AgentsFemaleHumansMaleNebivololQuality of LifeAntihypertensive AgentsNebivololantihypertensive drugsbeta-blockerserectile dysfunctionhypertensionnebivololsexual dysfunction

Identifiers

PMID37941540
PMCPMC10629452
OpenAlexW4388221129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.