Evidence map›Paper›PMID 37941514›Full record

ArticleThe European journal of neuroscience2024

Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's.

Katherine R Brimblecombe, Natalie Connor-Robson, Carole J R Bataille, Bradley M Roberts, Caitlin Gracie, Bethan O'Connor, Rebecca Te Water Naude, Gayathri Karthik, Angela J Russell, Richard Wade-Martins and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The European journal of neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Opto-chemogenetic inhibition of L-type CaCell reports methods · 2024
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Katherine R BrimblecombeDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0003-0809-7292
Natalie Connor-RobsonDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0001-8350-6928
Carole J R BatailleDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.ORCID 0000-0002-3963-0021
Bradley M RobertsDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0002-5192-2545
Caitlin GracieDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Bethan O'ConnorDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0002-0093-5688
Rebecca Te Water NaudeDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0002-1350-3163
Gayathri KarthikDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0003-1876-0975
Angela J RussellDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.ORCID 0000-0003-3610-9369
Richard Wade-MartinsDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0001-6691-580X
Stephanie J CraggDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.ORCID 0000-0001-9677-2256
University of Oxford · GB

Funding

Medical Research Council MR/N029453/1Parkinson's UK G-1803Parkinson's UK J-1403Wellcome TrustWellcome Trust 223202/Z/21/Z
6 · The paper itself

Abstract

Ca

Indexed as

DopamineParkinson Diseasealpha-SynucleinAnimalsCalciumCalcium Channels, L-TypeCorpus StriatumDopaminergic NeuronsFemaleIsradipineMaleMiceRisk FactorsSubstantia Nigraalpha-SynucleinCalciumCalcium Channels, L-TypeDopamineIsradipineCalb1dopamine D2 receptordopamine releasedopamine transporterL‐type calcium channelParkinson's diseasesex differencesstriatumsynuclein

Identifiers

PMID37941514
PMCPMC11426196
OpenAlexW4388535022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.