Evidence map›Paper›PMID 37940983›Full record

ArticleAnnals of clinical microbiology and antimicrobials2023

Catheter-related bloodstream infection caused by Tsukamurella tyrosinosolvens identified by secA1sequencing in an immunocompromised child: a case report.

Shinsuke Mizuno, Yoshiyuki Tsukamura, Shuro Nishio, Toshiaki Ishida, Daiichiro Hasegawa, Yoshiyuki Kosaka, Tadasuke Ooka, Junichiro Nishi, Masashi Kasai

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Infectious diseases & immunity · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shinsuke MizunoDivision of Infectious Disease, Department of Pediatrics, Hyogo Prefectural Kobe Children hospital, Kobe City, 6500047, Hyogo, Japan. 4t0121@gmail.com.ORCID http://orcid.org/0000-0003-0193-4916
Yoshiyuki TsukamuraDepartment of Inspection unit, Hyogo Prefectural Kobe Children hospital, Kobe City, Hyogo, Japan.
Shuro NishioDepartment of Hematology and Oncology, Hyogo Prefectural Kobe Children's Hospital, Kobe City, Hyogo, Japan.
Toshiaki IshidaDepartment of Hematology and Oncology, Hyogo Prefectural Kobe Children's Hospital, Kobe City, Hyogo, Japan.
Daiichiro HasegawaDepartment of Hematology and Oncology, Hyogo Prefectural Kobe Children's Hospital, Kobe City, Hyogo, Japan.
Yoshiyuki KosakaDepartment of Hematology and Oncology, Hyogo Prefectural Kobe Children's Hospital, Kobe City, Hyogo, Japan.
Tadasuke OokaDepartment of Microbiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Junichiro NishiDepartment of Microbiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Masashi KasaiDivision of Infectious Disease, Department of Pediatrics, Hyogo Prefectural Kobe Children hospital, Kobe City, 6500047, Hyogo, Japan.
Kobe Children's Hospital · JPKagoshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTsukamurella spp. are obligate aerobic, gram-positive, non-motile, and slightly acid-fast bacilli belonging to the Actinomycetes family. They share many characteristics with Nocardia, Rhodococcus, Gordonia, and the rapidly growing Mycobacterium species. Therefore, standard testing may misidentify Tsukamurella spp. as another species. Accurate and rapid diagnosis is critical for proper infection management, but identification of this bacterium is difficult in the standard laboratory setting. CASE PRESENTATION: A bloodstream infection caused by a gram-positive bacterium and related to a central venous catheter was identified in an immunocompromised 2-year-old girl. Tsukamurella tyrosinosolvens was identified by modified secA1 sequencing. Antibiotic treatment and removal of the central venous catheter resolved the infection. Inappropriate management of the catheter during an overnight stay outside of the hospital was considered as a possible source of infection.

conclusionsSecA1 sequencing may be a useful diagnostic tool in the identification of T. tyrosinosolvens. Providing proper central venous catheter care instructions to patients, their families, and medical staff is important for infection prevention.

Indexed as

ActinobacteriaActinomycetalesCatheter-Related InfectionsCentral Venous CathetersSepsisBacteria, AerobicChild, PreschoolFemaleHumansActinomycetesCatheter-related bloodstream InfectionMatrix-assisted laser desorption-ionization time-of-flight mass spectrometryPediatricsecA1 gene sequencingTsukamurella tyrosinosolvens

Identifiers

PMID37940983
PMCPMC10633952
OpenAlexW4388501048

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.