Evidence map›Paper›PMID 37940853›Full record

ArticleBMC psychiatry2023

The impact of anxiety, depression, and social support on the relationship between HIV-related stigma and mental health-related quality of life among Chinese patients: a cross-sectional, moderate-mediation study.

Yushu Zhang, Chengliang Chai, Jianjing Xiong, Lin Zhang, Jinlei Zheng, Zhen Ning, Ying Wang

Abstract read
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Stigma management, social support, and quality of life among adults with Crohn's disease and ulcerative colitis in Saudi Arabia: A cross-sectional study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
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  8. Attitudes toward partner notification ofFrontiers in public health · 2026
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  12. Observational
  13. Psychosocial Phenotype and Risky Sexual Behavior Among People Living with HIV in Changsha: A Latent Profile Analysis.International journal of sexual health : official journal of the World Association for Sexual Health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yushu Zhang *School of Public Health, Fudan University, Shanghai, China.
Chengliang Chai *Department of AIDS/STDs Control and Prevention, Zhejiang Provincial Center for Diseases Control and Prevention, Zhejiang Province, Hangzhou, China.
Jianjing XiongJing'an District Center for Disease Prevention and Control, Shanghai, China.
Lin ZhangCenter for Disease Control and Prevention, 10, East Section of Taihao Road, Henan Province, Zhoukou, 466000, China.
Jinlei ZhengZhejiang Provincial Center for Disease Control and Prevention, Zhejiang Province, Hangzhou, China.
Zhen NingDivision of Tuberculosis and AIDS Control and Prevent Shanghai Municipal Center for Disease Control and Prevention 1380, Zhongshan Xi Road, Shanghai, 200336, China. ningzhen@scdc.sh.cn.
Ying WangNHC Key Laboratory of Health Technology Assessment, Fudan University, Shanghai, China. wangying1013@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivePeople living with HIV (PLWH) are prone to mental health problems and evidence indicates that HIV-related stigma can negatively impact mental health-related quality of life. This study explored potential mechanisms between HIV-related stigma and mental health-related quality of life, specifically whether anxiety or depression mediates, and whether social support moderates, the relationship.

methodA total of 1197 Chinese PLWH participated in the study. The Berger HIV Stigma Scale, the Hospital Anxiety and Depression Scale (HADS), the 12-item Brief Health Survey (SF-12), and the Multidimensional Scale of Perceived Social Support (MSPSS) were employed.

resultsHIV-related stigma was negatively associated with mental health-related quality of life. Anxiety and depression partially mediated the relationship between HIV-related stigma and mental health-related quality of life; social support played a moderating role.

conclusionsThe mental health-related quality of life in PLWH was shown to be indirectly affected by HIV-related stigma through anxiety and depression in China. The negative impact of HIV-related stigma decreased with increased social support.

Indexed as

AnxietyDepressionHIV InfectionsQuality of LifeSocial StigmaCross-Sectional StudiesEast Asian PeopleHumansSocial SupportAnxietyDepressionHIV-related stigmaMental health-related quality of lifeSocial support

Identifiers

PMID37940853
PMCPMC10634100

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.