Evidence map›Paper›PMID 37940740›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2023

Metabolomics 2022 workshop report: state of QA/QC best practices in LC-MS-based untargeted metabolomics, informed through mQACC community engagement initiatives.

Warwick B Dunn, Julia Kuligowski, Matthew Lewis, Jonathan D Mosley, Tracey Schock, Candice Ulmer Holland, Krista A Zanetti, Dajana Vuckovic, Metabolomics Quality Assurance and Quality Control Consortium (mQACC)

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Warwick B DunnDepartment of Biochemistry, Cells and Systems Biology, Centre for Metabolomics Research, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7ZB, UK. warwick.dunn@liverpool.ac.uk.
Julia KuligowskiNeonatal Research Group, Health Research Institute La Fe, Avda. Fernando Abril Martorell 106, 46026, Valencia, Spain.
Matthew LewisBruker Life Sciences Mass Spectrometry, Bruker UK Ltd, Welland House, Longwood Close, Coventry, CV4 8AE, UK.
Jonathan D MosleyCenter for Environmental Measurement and Modeling, Environmental Protection Agency, Athens, GA, USA.
Tracey SchockChemical Sciences Division, National Institute of Standards and Technology (NIST), Charleston, SC, 29412, USA.
Candice Ulmer HollandEastern Laboratory, Office of Public Health Science (OPHS), Food Safety and Inspection Service (FSIS),, U.S. Department of Agriculture (USDA), Athens, GA, 30605, USA.
Krista A ZanettiOffice of Nutrition Research, Division of Program Coordination, Planning, and Strategic Initiatives, Office of the Director, National Institutes of Health, Bethesda, MD, USA.
Dajana VuckovicDepartment of Chemistry and Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montreal, QC, H4B 1R6, Canada.
Metabolomics Quality Assurance and Quality Control Consortium (mQACC)

Funding

Carlos III Health Institute CPII21/00003Fonds de Recherche du Quebec - Sante (FRQS) Chercheur Boursier Junior 2 grant 312947Intramural EPA EPA999999
6 · The paper itself

Abstract

introductionThe Metabolomics Quality Assurance and Quality Control Consortium (mQACC) organized a workshop during the Metabolomics 2022 conference.

objectivesThe goal of the workshop was to disseminate recent findings from mQACC community-engagement efforts and to solicit feedback about a living guidance document of QA/QC best practices for untargeted LC-MS metabolomics.

methodsFour QC-related topics were presented.

resultsDuring the discussion, participants expressed the need for detailed guidance on a broad range of QA/QC-related topics accompanied by use-cases.

conclusionsOngoing efforts will continue to identify, catalog, harmonize, and disseminate QA/QC best practices, including outreach activities, to establish and continually update QA/QC guidelines.

Indexed as

MetabolomicsTandem Mass SpectrometryChromatography, LiquidHumansQuality ControlAnalytical batchBlanksInternal standardsLiquid chromatography–mass spectrometry (LC–MS)MetabolomicsQuality control (QC) samplesSystem suitability testing (SST)

Identifiers

PMID37940740
PMCPMC11463686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.