Evidence map›Paper›PMID 37940737›Full record

ArticleObesity surgery2023

Impact of Nonalcoholic Fatty Liver Disease (NAFLD) on Weight Loss After Bariatric Surgery.

Mohammed Abu-Rumaileh, Raad A Haddad, Matheos Yosef, Nazanene H Esfandiari, Andrew Kraftson, Shafaq Khairi, Corey Lager, Jordan Bushman, Shoukoufeh Khalatbari, Monica Tincopa and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Mohammed Abu-RumailehDepartment of Internal Medicine, University of Toledo, Toledo, OH, USA.
Raad A HaddadDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Medicine, University of Michigan Medical School, 2800 Plymouth Road, NCRC 25-3696, Ann Arbor, MI, 48109, USA.
Matheos YosefBiostatistics Core, Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, USA.
Nazanene H EsfandiariDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Medicine, University of Michigan Medical School, 2800 Plymouth Road, NCRC 25-3696, Ann Arbor, MI, 48109, USA.
Andrew KraftsonDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Medicine, University of Michigan Medical School, 2800 Plymouth Road, NCRC 25-3696, Ann Arbor, MI, 48109, USA.
Shafaq KhairiDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Medicine, University of Michigan Medical School, 2800 Plymouth Road, NCRC 25-3696, Ann Arbor, MI, 48109, USA.
Corey LagerBronson Diabetes and Endocrinology, Homer Stryker, MD School of Medicine, Western Michigan University, Kalamazoo, MI, USA.
Jordan BushmanDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Medicine, University of Michigan Medical School, 2800 Plymouth Road, NCRC 25-3696, Ann Arbor, MI, 48109, USA.
Shoukoufeh KhalatbariBiostatistics Core, Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, USA.
Monica TincopaDivision of Gastroenterology and Hepatology, University of California at San Diego, La Jolla, CA, USA.
Oliver VarbanDepartment of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
Nadejda Bozadjieva-KramerDepartment of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
Elif A OralDivision of Metabolism, Endocrinology and Diabetes (MEND), Department of Medicine, University of Michigan Medical School, 2800 Plymouth Road, NCRC 25-3696, Ann Arbor, MI, 48109, USA. eliforal@med.umich.edu.ORCID 0000-0002-9171-1144
University of Michigan · USThomas Jefferson University · USUniversity of California San Diego · USUniversity of Toledo · USWestern Michigan University · US

Funding

The role of intestinal-derived FGF15/19 during obesity and rapid weight lossIK2BX005715 · VA · VETERANS HEALTH ADMINISTRATION · PI KRAMER, NADEJDA BOZADJIEVA · 2022 to 2025
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BLRD VA IK2 BX005715
6 · The paper itself

Abstract

objectiveObesity and associated comorbidities, such as NAFLD, impose a major healthcare burden worldwide. Bariatric surgery remains the most successful approach for sustained weight loss and the resolution of obesity-related complications. However, the impact of preexisting NAFLD on weight loss after bariatric surgery has not been previously studied. The goal of this study is to assess the impact of preexisting NAFLD on weight loss outcomes up to 5 years after weight loss surgery. RESEARCH DESIGN AND

methodsData from the Michigan Bariatric Surgery Cohort (MI-BASiC) was extracted to examine the effect of baseline NAFLD on weight loss outcomes. The cohort included a total of 714 patients older than 18 years of age undergoing gastric bypass (GB; 380 patients) or sleeve gastrectomy (SG; 334 patients) at the University of Michigan between January 2008 and November 2013. Repeated measure analysis was used to determine if preexisting NAFLD was a predictor of weight loss outcomes up to 5 years post-surgery.

resultsWe identified 221 patients with an established clinical diagnosis of NAFLD at baseline. Multivariable repeated measure analysis with adjustment for covariates shows that patients with preexisting NAFLD had a significantly lower percentage of total and excess weight loss compared to patients without preexisting NAFLD. Furthermore, our data show that baseline dyslipidemia is an indicator of the persistence of NAFLD after bariatric surgery.

conclusionsOur data show that patients' body weight loss in response to bariatric surgery is impacted by factors such as preexisting NAFLD. Additionally, we show that NAFLD may persist or recur in a subset of patients after surgery, and thus careful continued follow-up is recommended.

Indexed as

Bariatric SurgeryGastric BypassNon-alcoholic Fatty Liver DiseaseObesity, MorbidGastrectomyHumansObesityTreatment OutcomeWeight LossBariatric surgeryDyslipidemiaNonalcoholic fatty liver diseasePersistenceWeight loss

Identifiers

PMID37940737
PMCPMC12330159
OpenAlexW4388509207

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.