Evidence map›Paper›PMID 37940227›Full record

Observational studyThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2023

Association of Loneliness With Change in Physical and Emotional Health of Older Adults During the COVID-19 Shutdown.

Julianna Liu, Ray Yun Gou, Richard N Jones, Eva M Schmitt, Eran Metzger, Patricia A Tabloski, Franchesca Arias, Tammy T Hshieh, Thomas G Travison, Edward R Marcantonio and 2 more

Abstract readObservational Study
In one paragraph

Observational study in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Factors Associated With Shifts in Caregiving During COVID-19.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Julianna LiuAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA.
Ray Yun GouAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA.
Richard N JonesDepartment of Psychiatry and Human Behavior (RNJ), Brown University, Providence, RI.
Eva M SchmittAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA.
Eran MetzgerDepartment of Psychiatry (EM), Beth Israel Deaconess Medical Center, Boston, MA.
Patricia A TabloskiConnell School of Nursing (PAT), Boston College, Chestnut Hill, MA.
Franchesca AriasAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA; Harvard Medical School (FA, TTH, TGT, ERM, TF, SKI), Boston, MA; Department of Medicine (FA, TTH), Brigham and Women's Hospital, Boston, MA.
Tammy T HshiehAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA; Harvard Medical School (FA, TTH, TGT, ERM, TF, SKI), Boston, MA; Department of Medicine (FA, TTH), Brigham and Women's Hospital, Boston, MA.
Thomas G TravisonAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA; Harvard Medical School (FA, TTH, TGT, ERM, TF, SKI), Boston, MA.
Edward R MarcantonioHarvard Medical School (FA, TTH, TGT, ERM, TF, SKI), Boston, MA; Divisions of General Medicine and Gerontology (ERM), Beth Israel Deaconess Medical Center, Boston, MA.
Tamara FongAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA; Harvard Medical School (FA, TTH, TGT, ERM, TF, SKI), Boston, MA; Department of Neurology (TF), Beth Israel Deaconess Medical Center, Boston, MA. Electronic address: tfong@bidmc.harvard.edu.
Sharon K InouyeAging Brain Center (JL, RYG, EMS, FA, TTH, TGT, TF, SKI), Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA; Harvard Medical School (FA, TTH, TGT, ERM, TF, SKI), Boston, MA; Department of Medicine (SKI), Beth Israel Deaconess Medical Center, Boston, MA.

Funding

The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI SHAFI, MOUHSIN · 2010 to 2022
$26.7M
Development and Validation of a Delirium Severity ToolkitR01AG044518 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K., JONES, RICHARD N · 2014 to 2024
$7.3M
NIDUS III: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research inDeliriumR33AG071744 · NIA · JOHNS HOPKINS UNIVERSITY · PI John W. Devlin, Esther Seunghee Oh · 2021 to 2026
$4.7M
NIA NIH HHS P01 AG031720NIA NIH HHS R01 AG044518NIA NIH HHS R33 AG071744
6 · The paper itself

Abstract

objectivesTo examine factors influencing loneliness and the effect of loneliness on physical and emotional health, in the context of the COVID-19 pandemic.

designProspective, observational cohort.

settingCommunity-dwelling participants.

participantsOlder adults (n = 238) enrolled in a longitudinal study. MEASUREMENTS: Interviews were completed July-December 2020. Loneliness was measured with the UCLA 3-item loneliness scale. Data including age, marriage, education, cognitive functioning, functional impairment, vision or hearing impairment, depression, anxiety, medical comorbidity, social network size, technology use, and activity engagement were collected. Health outcomes included self-rated health, and physical and mental composites from the 12-item Short Form Survey. Physical function was measured by a PROMIS-scaled composite score.

resultsThirty-nine (16.4%) participants reported loneliness. Vulnerability factors for loneliness included age (RR = 1.08, 95% CI 1.02-1.14); impairment with instrumental activities of daily living (RR = 2.08, 95% CI 1.14-3.80); vision impairment (RR = 2.09, 95% CI 1.10-3.97); depression (RR = 1.34, 95% CI 1.25-1.43); and anxiety (RR = 1.92, 95% CI 1.55-2.39). Significant resilience factors included high cognitive functioning (RR = 0.88, 95% CI 0.83-0.94); large social network size (RR = 0.92, 95% CI 0.88-0.96); technology use (RR = 0.81, 95% CI 0.73-0.90); and social and physical activity engagement (RR = 0.91, 95% CI 0.85-0.98). Interaction analyses showed that larger social network size moderated the effect of loneliness on physical function (protective interaction effect, RR = 0.64, 95% CI 0.15-1.13, p <.01), and activity engagement moderated the effect of loneliness on mental health (protective interaction effect, RR = 0.65, 95% CI 0.25-1.05, p <.001).

conclusionsResilience factors may mitigate the adverse health outcomes associated with loneliness. Interventions to enhance resilience may help to diminish the detrimental effects of loneliness and hold great importance for vulnerable older adults.

Indexed as

COVID-19LonelinessActivities of Daily LivingAgedHumansLongitudinal StudiesMental HealthPandemicsProspective Studieshealth outcomeslonelinessolder adultsSocial isolation

Identifiers

PMID37940227
PMCPMC10797604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.