Evidence map›Paper›PMID 37939986›Full record

ArticleAmerican journal of ophthalmology2024

Outcomes and Complications 5 Years After Surgery for Pediatric Cataract Associated With Persistent Fetal Vasculature.

Kathryn M Haider, Michael X Repka, Desirae R Sutherland, Sarah R Hatt, Nicole Fallaha, Raymond T Kraker, B Michele Melia, Susan A Cotter, Jonathan M Holmes, Pediatric Eye Disease Investigator Group

Open access · greenAbstract read
In one paragraph

Article in American journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Kathryn M HaiderRiley Hospital for Children (K.M.H.), Indianapolis, Indiana, USA. Electronic address: pedig@jaeb.org.
Michael X RepkaWilmer Eye Institute (M.X.R.), Baltimore, Maryland, USA.
Desirae R SutherlandJaeb Center for Health Research (D.R.S., R.T.K., B.M.M.), Tampa, Florida, USA.
Sarah R HattMayo Clinic (S.R.H.), Rochester, Minnesota, USA.
Nicole FallahaCentre Hospitalier Universitaire Sainte-Justine (N.F.), Montreal, Quebec, Canada.
Raymond T KrakerJaeb Center for Health Research (D.R.S., R.T.K., B.M.M.), Tampa, Florida, USA.
B Michele MeliaJaeb Center for Health Research (D.R.S., R.T.K., B.M.M.), Tampa, Florida, USA.
Susan A CotterSouthern California College of Optometry (S.A.C.), Marshall B. Ketchum University, Fullerton, California, USA.
Jonathan M HolmesUniversity of Arizona-Tucson (J.M.H.), Tucson, Arizona, USA.
Pediatric Eye Disease Investigator Group
Jaeb Center for Health Research · USCentre Hospitalier Universitaire Sainte-Justine · CAMarshall B. Ketchum University · USMayo Clinic · USNational Eye Institute · USRiley Hospital for Children · USUniversity of Arizona · US

Funding

Pediatric Eye Disease Investigator Group Coordinating CenterU10EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI KRAKER, RAYMOND · 1997 to 2018
$75.2M
Pediatric Eye Disease Investigator Group NetworkUG1EY011751 · NEI · JAEB CENTER FOR HEALTH RESEARCH, INC. · PI Raymond Kraker, Stacy Pineles · 2019 to 2026
$53.7M
Pediatric Eye Disease Investigator Group: Chair's OfficeU10EY018810 · NEI · MAYO CLINIC ROCHESTER · PI HOLMES, JONATHAN M · 2009 to 2013
$3.5M
PEDIATRIC EYE DISEASE INVESTIGATOR GROUP: CHAIR'S OFFICEU10EY023198 · NEI · INDIANA UNIVERSITY INDIANAPOLIS · PI WALLACE, DAVID K · 2014 to 2018
$1.4M
NEI NIH HHS U10 EY011751NEI NIH HHS U10 EY018810NEI NIH HHS U10 EY023198NEI NIH HHS UG1 EY011751
6 · The paper itself

Abstract

purposeTo report 5-year outcomes after surgery for cataract associated with persistent fetal vasculature (PFV).

designClinical cohort study using pediatric cataract registry data collected annually from medical records.

methodsThis study included 64 children <13 years of age who were undergoing surgery for unilateral, nontraumatic cataract associated with PFV. Proportions with age-normal visual acuity (VA) and VA better than 20/200 at 5 years' follow-up were estimated. Cumulative incidences of complications and additional surgeries by 5 years were calculated. Outcomes were compared between eyes with unilateral PFV and eyes with unilateral non-PFV cataract from our registry.

resultsForty-eight of 64 eyes were aphakic postoperatively (median age at surgery 2 months [range 1-13 months]) and 16 were pseudophakic (29 months [range 2-92 months]). Overall, 4 of 42 eyes (10% [95% confidence interval {CI} 3%-23%]) achieved age-normal VA. VA better than 20/200 was achieved in 17 (59% [95% CI 39%-76%]) unilateral aphakic PFV eyes and 44 (43% [95% CI 32%-54%]) unilateral non-PFV aphakic eyes (age-adjusted odds ratio = 1.90 [95% CI 0.81-4.50]; P = .14). The most common complication in aphakic PFV eyes was glaucoma-related adverse events (cumulative incidence 24% [95% CI 9%-37%]). There was no significant difference in glaucoma-related adverse events between PFV and non-PFV eyes in aphakic participants ≤1 year of age at lensectomy (age-adjusted hazard ratio = 1.20 [95% CI 0.54-2.64], P = .66).

conclusionsA wide range of visual outcomes for PFV cataract were observed with a 10% probability of achieving age-normal VA. There was an ongoing risk for the development of glaucoma-related adverse events in PFV eyes.

Indexed as

CataractCataract ExtractionGlaucomaPersistent Hyperplastic Primary VitreousChildChild, PreschoolCohort StudiesFollow-Up StudiesHumansInfantPostoperative ComplicationsRetrospective StudiesVisual Acuity

Identifiers

PMID37939986
PMCPMC11005992
OpenAlexW4388440790

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.