ArticleRespiratory physiology & neurobiology2024
Age influences the specific force and fatigability of the external abdominal obliques but not pectoralis major muscles.
Article in Respiratory physiology & neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Relationship Between External Abdominal Pressure, and Respiratory and Physical Functions in Older Individuals Living in the Community.Australasian journal on ageing · 2026Article
- Structural and mitochondrial dendritic degenerations in old hypoglossal motor neurons.GeroScience · 2026Article
- Tongue blade neuromuscular junction defects in old F344 rats.Respiratory physiology & neurobiology · 2026Article
- Dendritic alterations precede age-related dysphagia and nucleus ambiguus motor neuron death.The Journal of physiology · 2025Article
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1 author at 1 institution in 1 country.
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Abstract
In the elderly, airway infections are associated with impaired airway defense behaviors, leading to an increased risk of airway infection. The muscles of the chest and abdominal wall are essential for performing effective airway defense manoeuvres, however, very little is known about their function in aging. Here in the 6- and 24-months old Fischer 344 rat model of aging, we assess the contractility and fatigability of chest (the pectoralis major muscle) and abdominal wall (external abdominal oblique) muscles. We assessed muscle function using an ex vivo approach, measuring isometric specific forces normalised to muscle CSA, via a platinum plate field stimulations at a range of frequencies (5-150 Hz) for 1 s. Surprisingly, we did not observe any effect of age on the specific force and fatigue properties of the pectoral muscle. However, in 24-months old rats, EAO specific force was reduced by ∼32 %. These finding suggest that not all respiratory muscles are equally vulnerable to age-associated weakness.
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