Evidence map›Paper›PMID 37938797›Full record

ReviewEuropean journal of human genetics : EJHG2024

A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection.

S Anand Narayanan, David A Jamison, Joseph W Guarnieri, Victoria Zaksas, Michael Topper, Andrew P Koutnik, Jiwoon Park, Kevin B Clark, Francisco J Enguita, Ana Lúcia Leitão and 10 more

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of human genetics : EJHG, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Circulating angiogenic progenitor cell apoptosis in Post-COVID-19 syndrome.International journal of cardiology. Heart & vasculature · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Molecular mechanisms of SARS-CoV-2 entry: implications for biomedical strategies.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 8 countries.

S Anand Narayanan *COVID-19 International Research Team, Medford, MA, 02155, USA. anarayan09@gmail.com.ORCID 0000-0002-9783-5711
David A Jamison *COVID-19 International Research Team, Medford, MA, 02155, USA.
Joseph W GuarnieriCOVID-19 International Research Team, Medford, MA, 02155, USA.
Victoria ZaksasCOVID-19 International Research Team, Medford, MA, 02155, USA.ORCID 0000-0001-7916-4902
Michael TopperCOVID-19 International Research Team, Medford, MA, 02155, USA.
Andrew P KoutnikHuman Healthspan, Resilience, and Performance, Florida Institute for Human and Machine Cognition, Pensacola, FL, 32502, USA.
Jiwoon ParkDepartment of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0003-0045-1429
Kevin B ClarkCOVID-19 International Research Team, Medford, MA, 02155, USA.
Francisco J EnguitaCOVID-19 International Research Team, Medford, MA, 02155, USA.
Ana Lúcia LeitãoMEtRICs, Department of Chemistry, NOVA School of Science and Technology, Universidade NOVA de Lisboa, 2829-516, Caparica, Portugal.
Saswati DasCOVID-19 International Research Team, Medford, MA, 02155, USA.ORCID 0000-0002-4548-0066
Pedro M Moraes-VieiraCOVID-19 International Research Team, Medford, MA, 02155, USA.ORCID 0000-0002-8263-786X
Diego GaleanoCOVID-19 International Research Team, Medford, MA, 02155, USA.
Christopher E MasonCOVID-19 International Research Team, Medford, MA, 02155, USA.ORCID 0000-0002-1850-1642
Nídia S TrovãoCOVID-19 International Research Team, Medford, MA, 02155, USA.ORCID 0000-0002-2106-1166
Robert E SchwartzCOVID-19 International Research Team, Medford, MA, 02155, USA.
Jonathan C SchislerCOVID-19 International Research Team, Medford, MA, 02155, USA.
Jordana G A Coelho-Dos-ReisCOVID-19 International Research Team, Medford, MA, 02155, USA.
Eve Syrkin WurteleCOVID-19 International Research Team, Medford, MA, 02155, USA.
Afshin BeheshtiCOVID-19 International Research Team, Medford, MA, 02155, USA. afshin.beheshti@nasa.gov.ORCID 0000-0003-4643-531X
Cornell University · USAtal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital · INBroad Institute · USChildren's Hospital of Philadelphia · USFlorida Institute for Human and Machine Cognition · USFlorida State University · USIowa State University · USJohns Hopkins University · USNational Institutes of Health · USUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Minas Gerais · BRUniversidade Nova de Lisboa · PTUniversidad Nacional de Asunción · PYUniversity for Peace · NLUniversity of Chicago · USUniversity of Lisbon · PTUniversity of North Carolina at Chapel Hill · US

Funding

Project 3: Serological Interactions with the Mucosal Innate Immune System Regulates COVID-19 Associated Tissue Damage.U54CA260543 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOLFGANG, MATTHEW C · 2020 to 2024
$9.8M
Assessing the Impact of SARS-CoV-2 on Adipose Tissue Function and Glucose HomeostasisR01DK132879 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI James C Lo, Robert E Schwartz · 2023 to 2026
$2.8M
Optimization of the engineered 3D hepatic microenvironment enhances pluripotent stem cell derived hepatocyteR01DK121072 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHWARTZ, ROBERT E · 2020 to 2024
$2.6M
NCI NIH HHS U54 CA260543NIDDK NIH HHS R01 DK121072NIDDK NIH HHS R01 DK132879
6 · The paper itself

Abstract

COVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and mortality worldwide. The betacoronavirus continues to evolve with global health implications as we race to learn more to curb its transmission, evolution, and sequelae. The focus of this review, the second of a three-part series, is on the biological effects of the SARS-CoV-2 virus on post-acute disease in the context of tissue and organ adaptations and damage. We highlight the current knowledge and describe how virological, animal, and clinical studies have shed light on the mechanisms driving the varied clinical diagnoses and observations of COVID-19 patients. Moreover, we describe how investigations into SARS-CoV-2 effects have informed the understanding of viral pathogenesis and provide innovative pathways for future research on the mechanisms of viral diseases.

Indexed as

COVID-19AnimalsHumansSARS-CoV-2

Identifiers

PMID37938797
PMCPMC10772081
OpenAlexW4388495106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.