Evidence map›Paper›PMID 37938566›Full record

ArticleNature communications2023

The alarmin IL33 orchestrates type 2 immune-mediated control of thymus regeneration.

Emilie J Cosway, Kieran D James, Andrea J White, Sonia M Parnell, Andrea Bacon, Andrew N J McKenzie, W E Jenkinson, Graham Anderson

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. The Ins and Outs of Thymic Epithelial Cell Differentiation and Function.Advances in experimental medicine and biology · 2025
    Review
  11. Article
  12. Generation and repair of thymic epithelial cells.The Journal of experimental medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emilie J CoswayInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Kieran D JamesInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.ORCID 0000-0001-8811-6996
Andrea J WhiteInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Sonia M ParnellInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.ORCID 0000-0002-4430-9072
Andrea BaconInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Andrew N J McKenzieMRC Laboratory of Molecular Biology, Cambridge, UK.
W E JenkinsonInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Graham AndersonInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK. g.anderson@bham.ac.uk.ORCID 0000-0002-2917-4085
University of Birmingham · GBMRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_U105178805Medical Research Council MR/N000919/1Medical Research Council MR/T029765/1
6 · The paper itself

Abstract

As the primary site of T-cell development, the thymus dictates immune competency of the host. The rates of thymus function are not constant, and thymus regeneration is essential to restore new T-cell production following tissue damage from environmental factors and therapeutic interventions. Here, we show the alarmin interleukin (IL) 33 is a product of Sca1

Indexed as

AlarminsInterleukin-33Immunity, InnateInterleukin-4LymphocytesAlarminsInterleukin-33Interleukin-4

Identifiers

PMID37938566
PMCPMC10632327
OpenAlexW4388492012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.