Evidence map›Paper›PMID 37938563›Full record

ArticleNPJ vaccines2023

IL6 suppresses vaccine responses in neonates by enhancing IL2 activity on T follicular helper cells.

Swetha Parvathaneni, Jiyeon Yang, Leda Lotspeich-Cole, Jiro Sakai, Robert C Lee, Mustafa Akkoyunlu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Inflammatory mediators of mRNA vaccine-induced adverse reactions in mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  3. State of pneumococcal vaccine immunity.Human vaccines & immunotherapeutics · 2024
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Swetha Parvathaneni *US FDA/CBER/OVRR/DBPAP, 10903, New Hampshire Ave., Silver Spring, MD, USA.
Jiyeon Yang *US FDA/CBER/OVRR/DBPAP, 10903, New Hampshire Ave., Silver Spring, MD, USA.
Leda Lotspeich-ColeUS FDA/CBER/OVRR/DBPAP, 10903, New Hampshire Ave., Silver Spring, MD, USA.
Jiro SakaiUS FDA/CBER/OVRR/DBPAP, 10903, New Hampshire Ave., Silver Spring, MD, USA.
Robert C LeeUS FDA/CBER/OVRR/DBPAP, 10903, New Hampshire Ave., Silver Spring, MD, USA.
Mustafa AkkoyunluUS FDA/CBER/OVRR/DBPAP, 10903, New Hampshire Ave., Silver Spring, MD, USA. Mustafa.Akkoyunlu@fda.hhs.gov.ORCID http://orcid.org/0000-0001-9958-4031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inability of neonates to develop CD4

Identifiers

PMID37938563
PMCPMC10632457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.