Evidence map›Paper›PMID 37938434›Full record

ArticleJournal of racial and ethnic health disparities2025

Cesarean Delivery Outcomes for Patients with Coronavirus Disease-2019 in the USA.

Michael Mazzeffi, David Miller, Ashley Garneau, Jessica Sheeran, Amanda Kleiman, Sachin H Mehta, Mohamed Tiouririne

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Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Michael MazzeffiDepartment of Anesthesiology, University of Virginia Health, PO Box 800710, Charlottesville, VA, 22908, USA. mmazzeff@virginia.edu.ORCID 0000-0003-2955-4915
David MillerUniversity of Virginia School of Medicine, Charlottesville, VA, USA.
Ashley GarneauDepartment of Anesthesiology, University of Virginia Health, PO Box 800710, Charlottesville, VA, 22908, USA.
Jessica SheeranDepartment of Anesthesiology, University of Virginia Health, PO Box 800710, Charlottesville, VA, 22908, USA.
Amanda KleimanDepartment of Anesthesiology, University of Virginia Health, PO Box 800710, Charlottesville, VA, 22908, USA.
Sachin H MehtaDepartment of Anesthesiology, University of Virginia Health, PO Box 800710, Charlottesville, VA, 22908, USA.
Mohamed TiouririneDepartment of Anesthesiology, University of Virginia Health, PO Box 800710, Charlottesville, VA, 22908, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCoronavirus disease-2019 (COVID-19) may have increased morbidity and mortality in patients having Cesarean delivery (CD) in the USA.

methodsWe performed a retrospective cohort study of patients who had CD in 2020 using the national inpatient sample. After stratification by COVID-19 status, demographics, comorbidities, complications, mortality, and costs were compared.

resultsThere were 31,444,222 hospitalizations in the USA in 2020 with a mortality rate of 2.8%. Among these, 1,453,945 patients had COVID-19 and mortality was 13.2%. There were 1,108,755 patients who had CD and 15,550 had COVID-19. Patients with COVID-19 more frequently had Medicaid and were Hispanic. Patients with COVID-19 had more comorbidities including chronic hypertension, diabetes mellitus, pre-eclampsia, and eclampsia. Mortality in CD patients with COVID-19 was 30 in 10,000 patients, while for non-COVID-19 patients, it was 1 in 10,000 patients, P < 0.001. The crude odds ratio for mortality in COVID-19 patients was 32.1 (95% confidence interval = 22.9 to 44.7), P < 0.001 and the adjusted odds ratio was 29.3 (95% confidence interval = 20.7 to 41.4), P < 0.001.

conclusionsCD patients with COVID-19 had 30-fold higher mortality before widespread vaccination was available with Hispanic and Medicaid patients disproportionately impacted. Potential explanations for this disparity include reduced access to personal protective equipment (e.g., masks) and testing, as well as socio-economic factors. Further research is needed to understand the factors that contributed to disparities in infection and clinical outcomes among obstetric patients during the COVID-19 pandemic. In future pandemics, enhanced efforts will be needed to protect economically disadvantaged women who are pregnant.

Indexed as

Cesarean SectionCOVID-19Pregnancy Complications, InfectiousAdultBlack or African AmericanComorbidityFemaleHispanic or LatinoHumansPregnancyRetrospective StudiesSARS-CoV-2United StatesWhiteYoung AdultCOVID-19DisparitiesObstetricsWomen’s health

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.